This article delivers a full insight into the concepts of social enterprise, social entrepreneurship, their sustainability issues and strategic understanding. Despite different nature, determinant factors, motivation and purpose, as well as orientation towards sustainable development of commercial and social enterprises the results of analysis show that both form of extant entrepreneurship could to stay together to successfully bridge, create synergy effect between social and commercial capital for the mutual development. However, the article revealed that in contrast to the commercial entrepreneurship, social entrepreneurship currently lacks and needs more strategic understanding (and its reflection in the reality) to be benefitted from in order to support overall sustainable entrepreneurship development in rural areas of Vietnam. Finally, the article proposed solutions to enhance social entrepreneurship and promote its expansion for the purpose of sustainable development.