2008
DOI: 10.1016/j.juro.2007.09.068
|View full text |Cite
|
Sign up to set email alerts
|

Coordinated Chemoradiation Therapy With Genital Preservation for the Treatment of Primary Invasive Carcinoma of the Male Urethra

Abstract: The chemoradiation therapy protocol is an alternative primary treatment modality for invasive urethral carcinoma. It enables an unprecedented potential for organ preservation.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
36
0
3

Year Published

2009
2009
2017
2017

Publication Types

Select...
4
3
2

Relationship

0
9

Authors

Journals

citations
Cited by 58 publications
(39 citation statements)
references
References 18 publications
0
36
0
3
Order By: Relevance
“…[3][4][5] Salvage surgery alone improves 5-year disease-free survival rates from 54% to 72%. 3,10 Multimodal treatment was planned for our patient. In spite of this, no additional treatment was carried out due to the patient's request and his other conditions.…”
Section: Discussionmentioning
confidence: 99%
“…[3][4][5] Salvage surgery alone improves 5-year disease-free survival rates from 54% to 72%. 3,10 Multimodal treatment was planned for our patient. In spite of this, no additional treatment was carried out due to the patient's request and his other conditions.…”
Section: Discussionmentioning
confidence: 99%
“…These are the patients who probably need the greatest effort in terms of a multidisciplinary approach to ensure the best clinical outcomes. Earlier reports of comparable cohorts emphasized a radiation-based approach (with or without surgery and/or chemotherapy) [3,1214]. However, those patients experienced significant radiation-related toxicity and, in addition, the studies contained relatively small numbers of patients and covered time spans as long as several decades, rendering decision-making regarding these patients difficult.…”
Section: Discussionmentioning
confidence: 99%
“…The following therapeutic options are currently available: surgical resection (often for distal and small urethral tumors), radiotherapy and chemotherapy (large tumors) for functional preservation of the penis, bladder and/or vagina), or a combination thereof in the case of more extensive tumors [10,[18][19][20]. Radical resections with urinary derivation [16] and partial resection with functional preservation of the urethra in cases of small injuries are among the surgical options [21].…”
Section: Discussionmentioning
confidence: 99%
“…Chemotherapy combined with local radiotherapy has also been used as primary treatment for organ preservation in tumors of the male urethra, especially in moderately or poorly differentiated squamous cell carcinoma [20][21][22][23][24].…”
Section: Discussionmentioning
confidence: 99%