Cooperative processing in primary somatosensory cortex and posterior parietal cortex during tactile working memory

Ku, Yixuan; Zhao, Di; Bodner, Mark; Zhou, Yong

doi:10.1111/ejn.12950

Cited by 16 publications

(12 citation statements)

References 52 publications

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“…On average, this S1 site was posterior to the M1 hotspot by 28 ± 8mm (Experiment 1) and 27 ± 7mm (Experiment 2). These distances, while offering no definitive assurance that S1 was targeted, fall within the range of analogous distances reported in previous studies presuming TMS over S1 [51,53,[57][58][59][60]. For TMS over the control site, the TMS coil was positioned 3cm above the inion on the midline with the handle pointing upward.…”

Section: Transcranialsupporting

confidence: 54%

Selective attention gates the interactive crossmodal coupling between perceptual systems

Convento

Rahman

Yau

2017

Preprint

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Cortical sensory systems often activate in parallel, even when stimulation is experienced through a single sensory modality [1][2][3]. Critically, the functional relationship between co-activated cortical systems is unclear: Co-activations may reflect the interactive coupling between information-linked cortical systems or merely parallel but independent sensory processing. Here, we report causal evidence consistent with the hypothesis that human somatosensory cortex (S1), which co-activates with auditory cortex during the processing of vibrations and textures [4][5][6][7][8][9], interactively couples to cortical systems that support auditory perception. In a series of behavioural experiments, we used transcranial magnetic stimulation (TMS) to probe interactions between the somatosensory and auditory perceptual systems as we manipulated attention state.Acute manipulation of S1 activity using TMS impairs auditory frequency perception when subjects simultaneously attend to auditory and tactile frequency, but not when attention is directed to audition alone. Auditory frequency perception is unaffected by TMS over visual cortex thus confirming the privileged interactions between the somatosensory and auditory systems in temporal frequency processing [10][11][12][13]. Our results provide a key demonstration that selective attention can modulate the functional properties of cortical systems thought to support specific sensory modalities. The gating of crossmodal coupling by selective attention may critically support multisensory interactions and feature-specific perception. Results and DiscussionAttending to a stimulus feature that can be redundantly signalled through different senses can activate multiple cortical sensory systems. For example, the auditory cortex can be activated by visual stimulation even in the absence of sounds, particularly when attending to stimulus features that are associated with sounds [14,15]. Such coactivation of sensory systems is thought to reflect a number of attention-based operations including the selection, refinement, and binding of sensory representations [16]. Critically, the functional relationship between co-activated cortical systems remains ambiguous. Co-activation could reflect an interactive coupling between the cortical sensory regions. Alternatively, co-activation could merely reflect the parallel, but independent activation of sensory systems. Distinguishing between these possibilities would provide critical insight into the functional role of distributed activity over cortical systems that are traditionally thought to be dedicated to unisensory processing.

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Section: Transcranialsupporting

confidence: 54%

Selective attention gates the interactive crossmodal coupling between perceptual systems

Convento

Rahman

Yau

2017

Preprint

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“…This suggests that, while BWM and EWM both involve maintenance of insula-mediated (i.e., visceral) body state representations, BWM may involve maintenance of parietal cortex-mediated (i.e., somatosensory/proprioceptive) body state representations to a greater degree than EWM. This is consistent with the previous studies of tactile WM reviewed in the “Introduction” section above ( Katus et al, 2015a , b ; Ku et al, 2015 ; Wu et al, 2018 ), which have demonstrated reliable engagement of prefrontal and somatosensory cortices (but not insular cortices) during maintenance of somatotopic information. It is also broadly consistent with previous work on the neural basis of empathy for pain ( Lamm et al, 2011 ), which has demonstrated that, while all empathic emotional experiences activate AI and anterior cingulate regions, the somatosensory cortex is only engaged when those empathic responses are triggered by directly viewing body parts in pain-promoting situations.…”

Section: Discussionsupporting

confidence: 92%

“…There have also been a few studies to date examining the WM maintenance of body-related information. For example, multiple studies have demonstrated that maintaining somatotopic information in WM (tactile WM) recruits somatosensory cortical regions and frontoparietal regions ( Katus et al, 2015a , b ; Ku et al, 2015 ; Wu et al, 2018 ), and that tactile WM appears to have attention-based rehearsal/maintenance mechanisms distinct from those underlying visual WM (VWM) ( Katus and Eimer, 2018 ). To our knowledge, however, no study to date has examined the ability to hold interoceptive information in WM.…”

Section: Introductionmentioning

confidence: 99%

Common and Unique Neural Systems Underlying the Working Memory Maintenance of Emotional vs. Bodily Reactions to Affective Stimuli: The Moderating Role of Trait Emotional Awareness

Smith

Lane

Sanova

et al. 2018

Front. Hum. Neurosci.

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Many leading theories suggest that the neural processes underlying the experience of one’s own emotional reactions partially overlap with those underlying bodily perception (i.e., interoception, somatosensation, and proprioception). However, the goal-directed maintenance of one’s own emotions in working memory (EWM) has not yet been compared to WM maintenance of one’s own bodily reactions (BWM). In this study, we contrasted WM maintenance of emotional vs. bodily reactions to affective stimuli in 26 healthy individuals while they underwent functional magnetic resonance imaging. Specifically, we examined the a priori hypothesis that individual differences in trait emotional awareness (tEA) would lead to greater differences between these two WM conditions within medial prefrontal cortex (MPFC). We observed that MPFC activation during EWM (relative to BWM) was positively associated with tEA. Whole-brain analyses otherwise suggested considerable similarity in the neural activation patterns associated with EWM and BWM. In conjunction with previous literature, our findings not only support a central role of body state representation/maintenance in EWM, but also suggest greater engagement of MPFC-mediated conceptualization processes during EWM in those with higher tEA.

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“…On average, this S1 target site was posterior to the M1 hotspot by 28±8mm (Experiment 1) and 27±7mm (Experiment 2). These distances, while offering no definitive assurance that S1 was targeted, fall within the range of analogous distances reported in previous studies presuming TMS over S1 [49,51,55–58]. For TMS over the control site, the TMS coil was positioned 3cm above the inion on the midline with the handle pointing upward.…”

Section: Methodsmentioning

confidence: 53%

Selective Attention Gates the Interactive Crossmodal Coupling between Perceptual Systems

2018

View full text Add to dashboard Cite

Sensory cortical systems often activate in parallel, even when stimulation is experienced through a single sensory modality [1-3]. Co-activations may reflect the interactive coupling between information-linked cortical systems or merely parallel but independent sensory processing. We report causal evidence consistent with the hypothesis that human somatosensory cortex (S1), which co-activates with auditory cortex during the processing of vibrations and textures [4-9], interactively couples to cortical systems that support auditory perception. In a series of behavioral experiments, we used transcranial magnetic stimulation (TMS) to probe interactions between the somatosensory and auditory perceptual systems as we manipulated attention state. Acute TMS over S1 impairs auditory frequency perception when subjects simultaneously attend to auditory and tactile frequency, but not when attention is directed to audition alone. Auditory frequency perception is unaffected by TMS over visual cortex, thus confirming the privileged interactions between the somatosensory and auditory systems in temporal frequency processing [10-13]. Our results provide a key demonstration that selective attention can modulate the functional properties of cortical systems thought to support specific sensory modalities. The gating of crossmodal coupling by selective attention may critically support multisensory interactions and feature-specific perception.

show abstract

Cooperative processing in primary somatosensory cortex and posterior parietal cortex during tactile working memory

Cited by 16 publications

References 52 publications

Selective attention gates the interactive crossmodal coupling between perceptual systems

Selective attention gates the interactive crossmodal coupling between perceptual systems

Common and Unique Neural Systems Underlying the Working Memory Maintenance of Emotional vs. Bodily Reactions to Affective Stimuli: The Moderating Role of Trait Emotional Awareness

Selective Attention Gates the Interactive Crossmodal Coupling between Perceptual Systems

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