Cooperative Effects in Copper Polyamidoamine Dendrimer Complexes Catalyzing the Reduction of Molecular Oxygen

Abstract

Affiliations [a] and [c] in the original article [1] are erroneous; the correct affiliations are given below.The Authors

EPR Characterization of Copper(II) Complexes of PAMAM-Py Dendrimers for Biocatalysis in the Absence and Presence of Reducing Agents and a Spin Trap

“…Table 1 shows the number of reactive Cu(II) ions determined from spectrophotometric titration. 17 Also, the number of Py groups is listed for each dendrimer.…”

“…So, on the basis of the EPR analysis, G5 dendrimer showed a peculiar interacting ability in respect to Cu(II) ions, due to the optimal distribution of Py groups at the external surface, which well justifies the highest value of Vmax found in previous studies. 17 Further information came from the magnetic parameters obtained by calculating the spectra. For the dendrimer− complex signal, the computations shown in parts (c) and (d) of Figure 3 were obtained for a Cu(II) concentration of 0.0025 M and the spectra were quite similar for all generations, characteristic of a Cu−Py 4 complex with a square planar structure, which was increasingly distorted by increasing generation.…”

“…In contrast, the active center in fifth and sixth generation dendrimers contained bicopper complexes. 17 These metallodendrimers not only have promising applications for biomedical uses, like anticancer and antiamyloidogenesis drugs and biocatalysts, but also constitute an excellent model and a platform to study interactions of Cu(II) in nanosized macromolecules. This study analyzes the complexation behavior of Cu(II) with PAMAM dendrimers functionalized with pyridine (Py) groups at the external surface from generation 2 to generation 6 (simply termed G2, G3, G4, G5, and G6), at different molar ratios between the ions and the dendrimer surface sites.…”