Cooled Needle Catheter Ablation Creates Deeper and Wider Lesions Than Irrigated Tip Catheter Ablation

Thiagalingam, Aravinda; Pouliopoulos, Jim; Barry, Michael A.; Boyd, Anita; Eipper, Vicki; Yung, Teresa; Ross, David L.; Kovoor, Pramesh

doi:10.1046/j.1540-8167.2005.40540.x

Cited by 23 publications

(22 citation statements)

References 18 publications

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“…13,37 Deep intramural circuits or foci may still be difficult to eliminate with available approaches. New technologies, such as needle-irrigated RF ablation, that allows deliver energy directly inside the myocardium, that are under investigation will be of interest in this regard 38,39 and systems for improved catheter navigation seem promising. 40 …”

Section: Methodsmentioning

confidence: 99%

Ventricular Tachycardia Ablation

Sacher

Tedrow

Field

et al. 2008

Circ: Arrhythmia and Electrophysiology

155

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Background-Evolving management of coronary artery disease, heart failure, and the use of implantable cardioverterdefibrillators impacts the characteristics of patients with recurrent ventricular tachycardia (VT). We investigated the substrate, procedure, and outcome evolution of all patients referred for VT ablation during the past 8 years. (17%) with NICMP died after a median of 13 months. Multivariate Cox regression analysis found that age, ejection fraction, and need for preprocedural mechanical hemodynamic support predicted mortality. Conclusions-The substrate causing VT in patients requiring ablation is evolving and determines the long-term outcome.In the setting of a normal heart, VT ablation is associated with a low risk of subsequent mortality, with no deaths occurring during a mean follow-up of Ͼ3 years. In contrast, in patients with SHD and recurrent VT, VT ablation can be helpful to suppress drug refractory VT, but long-term mortality remains significant. (Circ Arrhythmia Electrophysiol. 2008;1:153-161.)

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Section: Methodsmentioning

confidence: 99%

Ventricular Tachycardia Ablation

Sacher

Tedrow

Field

et al. 2008

Circ: Arrhythmia and Electrophysiology

155

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“…To avoid this phenomenon, the electrode tip should be cooled using water. On the basis of these results using a cooled-RFA for cardiac conduction disease [14,15], it is predicted that the lesion occurs in lung tissues away from the cooled-RFA. The cooled-RFA enables greater power output for a longer time compared with the standard noncooled-RFA, resulting in larger coagulation necrosis area.…”

Section: Resultsmentioning

confidence: 99%

Bronchoscopy-guided radiofrequency ablation as a potential novel therapeutic tool

Tsushima¹,

Koizumi²,

Tanabe³

et al. 2007

European Respiratory Journal

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The aim of the current study was to assess the safety of bronchoscopy-guided radiofrequency ablation (RFA) and compare the effectiveness between new internal cooled-RFA and standard noncooled-RFA.Normal lungs from sheep were used (n56). Internal cooled-RFA and standard noncooled-RFA were set to assess the most suitable RFA conditions, such as power output, flow rate and ablation time. Internal cooled-RFA was then applied under the most optimal conditions of power output and flow rate for 15, 30, 60 and 120 s, and two water temperatures either room temperature (RT) water or cold water. Criteria for the most appropriate conditions were set over 15 s of ablation time and 50uC of the tip's temperature.Internal cooled-RFA had no complications. Standard noncooled-RFA was complicated with bronchial bleeding after RFA. On the basis of the histological findings, average temperature and average output, the most appropriate conditions of the cooled-RFA were a power output of 30 W and flow rate of 30 or 40 mL?min -1. The cooled-RFA using cold water caused a smaller, more discrete, lesion compared with that using RT water.Bronchoscopy-guided internal cooled-radiofrequency ablation was an effective, safe and feasible procedure that could become a potential therapeutic tool in managing lung pathology.

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“…An intramural needle catheter has been developed to enable the creation of lesions deeper and wider than those of RF ablation. 77,78 A human feasibility study completed using this catheter in patients with recurrent VT resulted in at least one VT being terminated or noninducible. Complications included two cases of complete heart block and one of cardiac tamponade.…”

Section: Novel Ablation Modalities On the Horizonmentioning

confidence: 99%

Innovations in Clinical Cardiac Electrophysiology: Challenges and Upcoming Solutions in 2018 and Beyond

Vaidya¹,

Sugure²,

Asirvatham³

2017

J Innov Cardiac Rhythm Manage

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Cooled Needle Catheter Ablation Creates Deeper and Wider Lesions Than Irrigated Tip Catheter Ablation

Abstract: Cooled intramural needle ablation creates lesions that are significantly deeper and wider than endocardial RF ablation using an irrigated tip catheter in sheep hearts. This technology may be useful in treating ventricular tachycardia resistant to conventional ablation techniques.

Cited by 23 publications

References 18 publications

Ventricular Tachycardia Ablation

Ventricular Tachycardia Ablation

Bronchoscopy-guided radiofrequency ablation as a potential novel therapeutic tool

Innovations in Clinical Cardiac Electrophysiology: Challenges and Upcoming Solutions in 2018 and Beyond

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