Cooked mussels contaminated by Dinophysis sp.: A source of okadaic acid

Abstract

A method was developed for fractionation and isolation of toxic components present in extracts prepared from Dinophysis-contaminated mussels. The major toxin present in French mussels was identified as okadaic acid by its chromatographic properties and spectral data. Large amounts of mussel tissue (digestive glands and remaining meat) can be treated easily if they are cooked, or cooked and dried and are useful for isolating significant amounts of okadaic acid.

Uptake and fate of diarrhetic shellfish poisoning toxins from the dinoflagellate Prorocentrum lima in the bay scallop Argopecten irradians

“…Although toxin concentrations were relatively high in adult gonadal tissue, rapid detoxification rates again suggest that toxicity in the gonads was represented by a labile component confined to the intestinal tract, rather than bound to the tissue. This evidence agrees with observations for Mytilus edulis in which DSP toxin concentrations in digestive tissue were 7 (Vernoux et al 1994) to 10 times greater than that of the other tissues. Elimination rates of DSP toxins were lower for the viscera than for all other tissues.…”

Differential okadaic acid accumulation and detoxification by oysters and mussels during natural and simulated Dinophysis blooms

“…The contribution of non-visceral tissues to the total toxin burden ranged from 3 to 6 % in M. galloprovincialis (<1 % when calculated from concentrated extracts; [50]), and from 9 to 12.5 % in M. edulis [51,52]; however, it may be greater in other bivalve species such as the scallops Argopecten irradians (23 % [53]) and Pecten fumatus (78 % [48]). In our experiment, OA levels in non-visceral tissues were still undetectable in all bivalves after the initial 5 h of toxin uptake; however, their contribution to the total toxin burden increased to 9-13 % in P. perna, 16-23 % in C. gigas, and 23-34 % in C. brasiliana during the rest of the 24-h uptake period.…”