Convulsions: sodium fluoroacetate: a bibliographic review

Abstract

The use of pesticides is worldwide, especially in the areas of agricultural production in order to combat living beings harmful to production. The review aims to make the availability of essential information for the research area, on sodium fluoroacetate or FAS. For the development of this literature review, work was carried out through bibliographic research in articles and books on the subject addressed, following the methodology of exploratory study. A search for the online browser was performed by articles that contained keywords such as "convulsions", and "sodium fluoroacetate". It was observed that the mechanism of action of this compound is based on the transformation of fluoroacetate fluoroacetate, causing toxic and lethal effect on the body. Clinical signs can take between 30 minutes to 2 hours and 30 minutes to appear and depending on the species there will be a symptomatological variation in the animal. The diagnosis is based on the patient's clinical history, and there may be scarcity of diagnostic methods because the signals are not so evident. Sodium fluoroacetate therapy is done by attempting to block fluoroocrate action in the body. It is concluded that FAS poisoning involves multiple systems, which can have serious clinical consequences. Multifatorial poisoning by FAS, brings together a complexity of objectives, from cellular metabolism, and the variation sensitivity dose-species.