Conversion or Reversion of Interferon γ Release Assays for Mycobacterium tuberculosis Infection: A Systematic Review and Meta-analysis
Mao-Shui Wang,
Jarrod Li-Hunnam,
Ya-Li Chen
et al.
Abstract:Background
Interferon-gamma release assays (IGRA) are widely used for diagnosis of latent tuberculosis infection. However, with repeat testing, IGRA transformation (conversion or reversion) may be detected and is challenging to interpret. We reviewed the frequency of and risk factors for IGRA transformation.
Methods
We screened public databases for studies of human participants that reported the frequency of IGRA transformati… Show more
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