Abstract:Pyridine derivatives R 0380Conversion of Five-, Six-, and Seven-Membered Lactams to Racemic or Scalemic 2-Substituted Heterocycles by Amidoalkylation. -The process offers an efficient route to racemic and enantiopure 2-substituted pyrrolidines, piperidines, and azepanes. -(MADAN, S.; MILANO, P.; EDDINGS, D. B.; GAWLEY*, R. E.; J. Org. Chem. 70 (2005) 8, 3066-3071; Dep. Chem. Biochem., Univ. Ark., Fayetteville, AR 72701, USA; Eng.) -Jannicke 37-138
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