Conversion of 5-Hydroxymethylfurfural into 6-(Hydroxymethyl)pyridin-3-ol: A Pathway for the Formation of Pyridin-3-ols in Honey and Model Systems

Hidalgo, Francisco J.; Lavado-Tena, Cristina M.; Zamora, Rosario

doi:10.1021/acs.jafc.0c01679

Cited by 2 publications

(1 citation statement)

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“…During the thermal processing of food, large amounts of α‐DCs and the abovementioned hazardous substances are generated. Although much research has indicated that α‐DCs are useful indicators of the degree of heat treatment (Hidalgo et al., 2020; Nikolov & Yaylayan, 2011; Zhao et al., 2021), few attempts have been made to develop indexes for acrylamide, furan, ALEs, and AGEs using the corresponding α‐DCs as proxies. Above all, it is necessary to accurately determine the contents of α‐DCs in foods to clarify their relationships with these hazardous substances.…”

Section: Introductionmentioning

confidence: 99%

α‐Dicarbonyl compounds in food products: Comprehensively understanding their occurrence, analysis, and control

Yan

Xue

2023

Comp Rev Food Sci Food Safe

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α-Dicarbonyl compounds (α-DCs) are readily produced during the heating and storage of foods, mainly through the Maillard reaction, caramelization, lipidperoxidation, and enzymatic reaction. They contribute to both the organoleptic properties (i.e., aroma, taste, and color) and deterioration of foods and are potential indicators of food quality. α-DCs are also important precursors to hazardous substances, such as acrylamide, furan, advanced lipoxidation end products, and advanced glycation end products, which are genotoxic, neurotoxic, and linked to several diseases. Recent studies have indicated that dietary α-DCs can elevate plasma α-DC levels and lead to "dicarbonyl stress." To accurately assess their health risks, quantifying α-DCs in food products is crucial. Considering their low volatility, inability to absorb ultraviolet light, and high reactivity, the analysis of α-DCs in complex food systems is a challenge. In this review, we comprehensively cover the development of scientific approaches, from extraction, enrichment, and derivatization, to sophisticated detection techniques, which are necessary for quantifying α-DCs in different foods. Exposure to α-DCs is inevitable because they exist in most foods. Recently, novel strategies for reducing α-DC levels in foods have become a hot research topic. These strategies include the use of new processing technologies, formula modification, and supplementation with α-DC scavengers (e.g., phenolic compounds). For each strategy, it is important to consider the potential mechanisms underlying the formation and removal of process contaminants. Future studies are needed to develop techniques to control α-DC formation during food processing, and standardized approaches are needed to quantify and compare α-DCs in different foods.

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Section: Introductionmentioning

confidence: 99%