Conversion Infrastructure for Maintaining High Availability of Web Services Using Multiple Service Providers

Melliar-Smith, P. M.; Moser, Louise E.

doi:10.1109/icws.2015.110

Cited by 4 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Weaver et al ( 2005 ) have demonstrated that treatment with the amino acid L-methionine, a methyl group donor, in adulthood normalized methylation patterns of the GR gene and normalized HPA axis activity in rats that experienced low levels of maternal nurturing behaviors. GRs are widely expressed in microglia, oligodendrocytes, and astrocytes (Vardimon et al, 1999 ; Melliar-Smith and Moser, 2015 ). Microglial function and activation are regulated in part by glucocorticoid (GC) binding (Melliar-Smith and Moser, 2015 ).…”

Section: Targeted Treatment Interventions For Ela Exposure: Preclinical and Clinical Findingsmentioning

confidence: 99%

“…GRs are widely expressed in microglia, oligodendrocytes, and astrocytes (Vardimon et al, 1999 ; Melliar-Smith and Moser, 2015 ). Microglial function and activation are regulated in part by glucocorticoid (GC) binding (Melliar-Smith and Moser, 2015 ). GCs regulate the maturation and myelinating activity of OLs, however, direct involvement of GRs is lacking.…”

Section: Targeted Treatment Interventions For Ela Exposure: Preclinical and Clinical Findingsmentioning

confidence: 99%

See 1 more Smart Citation

Glia-Driven Brain Circuit Refinement Is Altered by Early-Life Adversity: Behavioral Outcomes

Milbocker

Campbell

Collins

et al. 2021

Front. Behav. Neurosci.

View full text Add to dashboard Cite

Early-life adversity (ELA), often clinically referred to as “adverse childhood experiences (ACE),” is the exposure to stress-inducing events in childhood that can result in poor health outcomes. ELA negatively affects neurodevelopment in children and adolescents resulting in several behavioral deficits and increasing the risk of developing a myriad of neuropsychiatric disorders later in life. The neurobiological mechanisms by which ELA alters neurodevelopment in childhood have been the focus of numerous reviews. However, a comprehensive review of the mechanisms affecting adolescent neurodevelopment (i.e., synaptic pruning and myelination) is lacking. Synaptic pruning and myelination are glia-driven processes that are imperative for brain circuit refinement during the transition from adolescence to adulthood. Failure to optimize brain circuitry between key brain structures involved in learning and memory, such as the hippocampus and prefrontal cortex, leads to the emergence of maladaptive behaviors including increased anxiety or reduced executive function. As such, we review preclinical and clinical literature to explore the immediate and lasting effects of ELA on brain circuit development and refinement. Finally, we describe a number of therapeutic interventions best-suited to support adolescent neurodevelopment in children with a history of ELA.

show abstract

Section: Targeted Treatment Interventions For Ela Exposure: Preclinical and Clinical Findingsmentioning

confidence: 99%

Section: Targeted Treatment Interventions For Ela Exposure: Preclinical and Clinical Findingsmentioning

confidence: 99%

Glia-Driven Brain Circuit Refinement Is Altered by Early-Life Adversity: Behavioral Outcomes

Milbocker

Campbell

Collins

et al. 2021

Front. Behav. Neurosci.

View full text Add to dashboard Cite

show abstract

“…For ensuring availability in the presence of service failures, there are mechanisms that allow to call an alternative service if the currently called service fails [24]. Even though this decouples the availability of the workflow execution from the availability of a specific service, the technique cannot tolerate the failure of the device on which the workflow is being executed.…”

Section: Related Workmentioning

confidence: 99%

Exploring the Search Space Between Active and Passive Workflow Replication

Schafer

Rothermel

Tariq

2017

2017 IEEE 10th Conference on Service-Oriented Computing and Applications (SOCA)

View full text Add to dashboard Cite

Today, workflows are executed in heterogeneous environments, such as the Internet, to automate interactions with services of business partners and other third parties. In such heterogeneous environments, device and communication failures occur frequently. These failures might delay or even stop the workflow executions rendering the workflow unavailable. For ensuring availability, workflow executions are replicated on multiple devices allowing the workflow execution to continue even if some of the devices fail. So far, two workflow replication mechanisms have been proposed: active and passive replication. While active replication incurs high cost in terms of compensation even for failure free executions, passive replication provides lower availability than active replication. In this paper, we propose a new replication mechanism called partitiontolerant replication that combines the benefits of active and passive replication. Our evaluations on OpenStack show that partition-tolerant replication imposes no compensation cost for failure free executions like passive replication while providing availability close to active replication.

show abstract

“…Other approaches improve availability by providing the functionality to switch from a used service that is failed to an alternative service [24], [25]. Some approaches even call multiple alternative services in parallel and use the first reply they receive and cancel or compensate the other executions [26], [27].…”

Section: Related Workmentioning

confidence: 99%

HAWKS: A System for Highly Available Executions of Workflows

Schafer

Weiß

Tariq

et al. 2016

2016 IEEE International Conference on Services Computing (SCC)

View full text Add to dashboard Cite

The workflow technology is the de facto standard for managing business processes. Today, workflows are even used for automating interactions and collaborations between business partners, e.g., for enabling just-in-time production. Every workflow that is part of such a collaboration needs to be highly available. Otherwise, the business operations, e.g., the production, might be hindered or even stopped. Since today's business partners are scattered across the globe, the workflows are executed in a highly distributed and heterogeneous environment. Those environments are, however, failure-prone and, thus, providing availability is not trivial. In this work, we improve availability by replicating workflow executions, while ensuring that the outcome is the same as in a non-replicated execution. For making workflow replication easily usable with current workflow technology, we derive the requirements for modeling a workflow replication system. Then, we propose the HAWKS system, which adheres to the previously specified requirements and is compatible with current technology. We implement a proof-of-concept in the open-source workflow execution engine Apache ODE for demonstrating this compatibility. Finally, we extensively evaluate the impact of using HAWKS in terms of performance and availability in the presence of failures.

show abstract

Conversion Infrastructure for Maintaining High Availability of Web Services Using Multiple Service Providers

Cited by 4 publications

References 11 publications

Glia-Driven Brain Circuit Refinement Is Altered by Early-Life Adversity: Behavioral Outcomes

Glia-Driven Brain Circuit Refinement Is Altered by Early-Life Adversity: Behavioral Outcomes

Exploring the Search Space Between Active and Passive Workflow Replication

HAWKS: A System for Highly Available Executions of Workflows

Contact Info

Product

Resources

About