Convergent Dendrons and Dendrimers:  from Synthesis to Applications

Abstract

I. Introduction 3819 A. Structure 3820 B. Applications 3821 C. Synthetic Approaches 3821 1. Divergent Approach 3821 2. Convergent Approach 3822 D. Features of the Convergent Synthesis 3823 1. Structural Purity 3823 2. Synthetic Versatility 3823 II. Convergent Synthesis of Dendrons and Dendrimers 3824 A. Single-Stage Convergent Syntheses 3824 1. Poly(aryl ether) Dendrimers 3824 2. Poly(aryl alkyne) Dendrimers 3826 3. Poly(phenylene) Dendrimers 3827 4. Poly(alkyl ester) Dendrimers 3827 5. Poly(aryl alkene) Dendrimers 3828 6. Poly(alkyl ether) Dendrimers 3828 7. Other Convergent Dendrimer Syntheses 3829 B. Accelerated Approaches 3829 1.

New methodologies in the construction of dendritic materials

“…The preparation of very large dendrimers (Z G6) is complicated utilizing this approach and only gives rise to small amounts of material. 23 The most attractive feature of the convergent method is the ability to prepare well-defined, bifunctional dendrimers, where two dendrons exhibit multiple groups of different functionality. …”

Dendrimers: A Review on Synthetic Approaches

“…Convergent approach (Grayson and Frechet, 2001) of dendrimer synthesis overcomes the purity and structural defect issues of divergent synthesis. By this approach more uniform and symmetric dendrimers can be synthesized but with lower overall yield.…”

“…Polyether dendrimer Frechet (Grayson and Frechet, 2001) There are different dendrimer families with different synthetic routes but common in all is repeated sequence reactions and their purification steps. These dendrimer families are summarized in table 1.…”

Dendrimer porphyrin-based self-assembled nano-devices for biomedical applications

“…20,21 Because porphyrin and phthalocyanine have unique photofunctional properties, such as a large absorption cross-section, fluorescence emission, and photosensitizing properties, DP and DPc can be used as photofunctional nano-devices. [22][23][24][25] Upon excitation by light, porphyrin and phthalocyanine can fluoresce or transfer their excitation energy or an electron to an appropriate acceptor molecule.…”