Conventional, diffusion, and permeability MR findings in ocular medulloepithelioma

Abstract

Conventional MR findings were similar to previously reported cases. Mean ADCs were moderately high. TICs showed slow increase and presence of wash out. K-trans, AUC, VE, and TME were higher in teratoid variants. Permeability parameters in differential diagnosis with lesions mimicking medulloepithelioma need further investigations.

Ciliary body medulloepithelioma treated with intra-operative brachytherapy after fine needle aspiration biopsy

“…Contrary to retinoblastomas, medulloepitheliomas are most often located in the peripheral retina and do not present calcifications. Intra-tumoral cysts have been shown in 50% of cases [9], and MRI typically reveals a ciliary body mass that is iso-hyperintense to vitreous on T1 and hypointense on T2 [10,11], which would be consistent with our radiologic findings. Moreover, as tumor can extend into the anterior chamber, it can be misdiagnosed as iris xanthogranuloma.…”

Medulloepithelioma in newborn: Advanced clinical status

“…Medulloepithelioma can be categorized into teratoid and non-teratoid types, each of which can be subclassified as benign or malignant. 9 Regarding the histopathology of our cases, there is the confirmed diagnosis of a malignant medulloepithelioma that was teratoid in 2 out of 3 cases in association with intralesional necrosis and hemorrhages, while one was non-teratoid.…”

“…Therefore many patients are treated for secondary effectsbefore thetumor mass is discovered. 1,9 Our cases, however, share the same advanced and critical clinical status.…”

“…Cryotherapy may play a role in small tumors or in limited small relapses. 1,9 Our cases underwent enucleation due to the advanced clinical stage characterized by a big mass filling the entire vitreous chamber, and to the risk of local invasion and systemic diffusion of the tumor.…”