Convenient and Efficient Triton B–Mediated Synthesis of Functionalized Oxime Ethers

Triton B Catalyzed Rapid and Mild Synthetic Protocol for both Henry Reaction of Isatin and Michael Reaction of Chalcone with Nitroalkane

“…36 Therefore, Triton B serves as a 'green' alternative in many reactions. [37][38][39] As shown in previous reports, as an excellent organic base, Triton B can be used as a reagent for alkylation, 40 epoxide cleavage, 41 synthesis of oxime ethers, 42 nitro aldol condensation, 43 and also as a phase-transfer catalyst for rapid reactions by helping in solubilize the reactants in a uniform medium. 44 When Triton B is absorbed in fly ash it acts as an excellent base catalyst for the Deobnar reaction, the Baker-Venkataraman reaction, and the Knoevenagel reaction.…”

Photophysical behavior of a new cholesterol attached coumarin derivative and fluorescence spectroscopic studies on its interaction with bile salt systems and lipid bilayer membranes

“…Synthesis of Cum-Chl was achieved by a three-step protocol with the Blaise reaction in the key step (Scheme 1). Michael addition of cholesterol 3 to acrylonitrile in the presence of a catalytic amount of Triton B [27][28][29] (benzyltrimethyl ammonium hydroxide) as base provided 3-cholesterylpropionitrile 4 in good yield. The nitrile 4 was subjected to Blaise reaction with ethyl bromoacetate using Zn in the presence of a catalytic amount of TMSCl followed by hydrolysis of the zinc complex with 3 N HCl to provide the b-keto ester 5.…”

A Concise, Metal‐Free Approach to the Synthesis of Oxime Ethers from Cross‐Dehydrogenative‐Coupling of sp3 C–H Bonds with Oximes

“…Direct synthesis of oxime ethers from unactivated alkenes catalyzed by cobalt was reported by Carreira 13. Although these methods are efficient, they have the drawback of using a metal catalyst, which generates metal‐ion‐containing waste 14…”