Controversies and challenges in fibromyalgia: a review and a proposal

Cohen, Helen

doi:10.1177/1759720x17699199

Cited by 57 publications

(57 citation statements)

References 110 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Criteria put forward from 1990, 2010, and 2016 revision of 2010/2011 are useful to diagnose FM. 3,4 Diagnostic delay of mean period of 2.3 years is common. FM does not have a definite objective evidence and diagnosis is based on clinical criteria.…”

Section: Introductionmentioning

confidence: 99%

Burden of Illness Due to Fibromyalgia in a Neurology Clinic

Vijayan

Nair

Geethadevi

2020

JNRP

View full text Add to dashboard Cite

Background Fibromyalgia (FM) is a common disorder in general population and it causes an increased patient load in hospitals and specialty clinics. FM attendance will be high in clinics dealing with neuropathic pain and other pain syndromes. Though prevalence of FM has been studied in community and pain clinics in other countries, it has not so far been studied in India. So, a study is relevant and hence it was planned in neurology clinic of a teaching government hospital. At present, they are treated mainly by nonsteroidal anti-inflammatory drugs (NSAIDs) which are public health hazard. Methods Using 2016 revision of 2010/2011 American College of Rheumatology criteria of FM, patients were screened in neurology OPD. Proportion and clinical profile were noted. Study was continued for 6 months till the sample size was met. Results A total of 2,300 patients were screened. Two hundred and ninety-eight FM patients were identified among them. Proportion was 12.96%. Delayed diagnosis of more than a year occurred in 55%. Only 29.2% were treated, but none was offered cognitive behavioral therapy (CBT) before. NSAIDs for pain were given for 51.01%. Conclusion Proportion of FM detected is considerable. Affection of homemakers and manual laborers, delayed diagnosis, coexisting comorbid illness, and treatment of pain with NSAIDs are causes of concern. Clinicians should be sensitized to clinical profile and criteria of FM. Patients should be diagnosed and treated by CBT at the earliest and NSAIDs should be avoided as far as possible.

show abstract

Section: Introductionmentioning

confidence: 99%

Burden of Illness Due to Fibromyalgia in a Neurology Clinic

Vijayan

Nair

Geethadevi

2020

JNRP

View full text Add to dashboard Cite

show abstract

“…Bu gelişmeler ışığında artık, FMS'nin artık, santral sensitizasyona bağlı kronik yaygın ağrı spektrumunun en uç örneği kabul edilmesi gerektiği görüşü yaygınlaşmaktadır (17)(18)(19).…”

Section: Tanım Ve Tanı Kriterleriunclassified

The role of fibromyalgia in rheumatic diseases

2019

Ege Tıp Dergisi

View full text Add to dashboard Cite

Romatolojik hastalıklarda fibromiyaljinin payı The role of fibromyalgia in rheumatic diseases Arzu On Ege Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı Öz Fibromiyalji sendromu (FMS), kronik yaygın kas-iskelet ağrısı, yaygın hassas noktalar, multipl somatik ve bilişsel problemlerle karakterize, spesifik laboratuvar ve görüntüleme bulgusu olmayan klinik bir sendromdur. Kronik romatolojik hastalıklarda FMS prevalansının genel popülasyona göre daha yüksek olduğu gösterilmiştir. Komorbid FMS hastalık aktivite skorlarının yükselmesine, dolayısıyla romatolojik hastalığın şiddetinin yanlış değerlendirilmesine ve gereksiz tedavilerin verilmesine neden olabilir. Bu nedenle eşlik eden FMS'nun tanınması, romatolojik hastalığın optimal tedavisi için önem taşır. Komorbid FMS olan olgularda hastalık aktivite göstergeleri dikkatle yorumlanmalı, objektif klinik ölçütler göz önünde bulundurulmalıdır. Bu derlemede, değişik romatolojik hastalıklarda komorbid FMS prevalansı, patofizyolojisi ve altta yatan inflamatuvar hastalık üzerindeki etkileri gözden geçirilecektir.

show abstract

“…The understanding of FM has changed from a predominantly peripheral musculoskeletal pathology to a centralized pain state, a maladaptive pain amplification through a variety of different mechanisms. This does not deny the contribution of peripheral nociceptive mechanisms, but these individuals feel more pain than would normally be expected based on the degree of nociceptive input . Recent studies have shown that FM is influenced by both genetics and epigenetics, and it is triggered by environmental factors, stress, and physical or emotional trauma .…”

Section: Introductionmentioning

confidence: 98%

Fibromyalgia, sleep disturbance and menopause: Is there a relationship? A literature review

et al. 2019

View full text Add to dashboard Cite

Introduction Fibromyalgia (FM) symptoms worsen in a significant portion of patients with the onset of menopause. Some patients report that their symptoms begin after menopause, suggesting a relationship between these entities. Sleep disturbance is a common condition in FM and menopause, and it is associated with chronic pain. Methods/Objectives Several electronic databases were searched, from the first available year to April 2018 to evaluate the publications that assessed the effects of menopause and sleep disturbance on the appearance or worsening of FM and the role of hormone therapy for these patients. Results The results are summarized in three tables. The objective sleep patterns of FM patients included high sleep latency, frequent arousals and intrusion of alpha wave sleep and NREM (non‐rapid eye movement) sleep in delta sleep. Poor sleep during menopause is more frequent in late perimenopause and surgical menopause, and may be related to vasomotor symptoms or not. Hormone therapy exerted a positive effect on subjective sleep quality of symptomatic menopausal women. Studies have shown a high association between FM and early and surgical menopause. Raloxifene exerted a positive effect on pain and sleep in FM patients; however one study that analyzed the effects of transdermal estrogen therapy found no improvement in subjective and objective parameters of pain. Conclusion Further studies are needed to elucidate the nature of the association between menopause, sleep and persistent pain syndromes, such as FM, showing the role of hormone therapy in prospective placebo‐controlled trials.

show abstract

Controversies and challenges in fibromyalgia: a review and a proposal

Cited by 57 publications

References 110 publications

Burden of Illness Due to Fibromyalgia in a Neurology Clinic

Burden of Illness Due to Fibromyalgia in a Neurology Clinic

The role of fibromyalgia in rheumatic diseases

Fibromyalgia, sleep disturbance and menopause: Is there a relationship? A literature review

Contact Info

Product

Resources

About