A procedure for establishing equivalence classes in a participant with Down syndrome was implemented. The classes were composed of written words (A), pictorial representations (B), digit numbers (C), and auditory words (D) representing metro stations. In the training phase we implemented a successful procedure for enhancing perceptual discrimination of written words when presented as sample stimuli (A), and we established a reduced number of stimulus relations: AB, BC, DA, from which the participant was able to derive full stimulus classes that included derived relations between stimuli that had not 1.