Controlling perinatally acquired hepatitis B

Abass, Fuad; Thomas, Ramani D.; Rajkumar, Abinayaa; Gupta, Nidhi; Puliyel, Jacob

doi:10.1007/bf02721853

Cited by 6 publications

(4 citation statements)

References 3 publications

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“…Since their center is also a tertiary care center, it might have been possible that many of the HBsAg positive patients might have been referred to hospital resulting in a referral bias. In the second study conducted in 2001 [Abass et al, 2001], 6,910 pregnant women were screened, and the HBsAg positivity rate was 1%. In a later study, the same group [Varghese et al, 2004] screened 6,341 pregnant women and found the HBsAg prevalence of 0.8%.…”

Section: Discussionmentioning

confidence: 99%

“…About 12 studies in the Indian subcontinent have looked specifically at the prevalence of HBsAg positivity in the pregnant women. However, only four studies were sufficiently large, with adequate number of women screened, to reach a meaningful conclusion, yet, the results are conflicting [Nayak et al, 1987; Abass et al, 2001; Varghese et al, 2004; Sandesh et al, 2006]. In addition, HBV infection in pregnant women is mostly asymptomatic and therefore the disease burden is likely to be under appreciated.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India

Pande

Sarin

Patra

et al. 2011

Journal of Medical Virology

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A large program was conducted by the Government of India to study the prevalence and profile of chronic hepatitis B virus (HBV) infection and its risk factors in pregnant women attending a tertiary care hospital in India. From September 2004 to December 2008 consecutive pregnant women attending the antenatal clinic were screened and those found positive for HBsAg were enrolled. Healthy non-pregnant women of child-bearing age, who presented for blood donation during the same period, served as controls. Women with symptoms of liver disease or those aware of their HBsAg status were excluded. Of the 20,104 pregnant women screened, 224 (1.1%) and of the 658 controls, 8 (1.2%) were HBsAg positive (P = ns). Previous blood transfusions and surgery were significant risk factors for infection with HBV. Of the women who were HBsAg positive, the ALT levels were normal in 54% of the women and HBV DNA levels were above 2,000 IU/ml in 71% of women. The median HBV DNA levels were higher in women who were HBeAg positive compared to the HBeAg negative group. The most common HBV genotype was D (84%) followed by A + D and A (8% each). In conclusion, the prevalence of HBsAg positivity among asymptomatic pregnant women in North India is 1.1% with 71% having high HBV DNA levels. These women may have a high risk of transmitting infection to their newborns.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India

Pande

Sarin

Patra

et al. 2011

Journal of Medical Virology

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show abstract

“…However, only very few studies were sufficiently large, with adequate number of females screened, to reach a meaningful conclusion. In one old study, HBsAg positivity in pregnant female was 3.7% in 1987 [95] and 1% in 1999 in North India [96]. More recent studies have found lower HBsAg prevalence in pregnant females: 0.25% in 2006 in South India [97] and 1.1% (2004-2008) in North India [98].…”

Section: Central Asia (Afghanistan Kazakhstan Kyrgyzstan Tajikistan T...mentioning

confidence: 99%

Asian Pacific association for the study of liver (APASL) guidelines: hepatitis B virus in pregnancy

et al. 2022

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Hepatitis B virus (HBV) infection still remains a major public health issue in the Asia-Pacific region. Most of the burden of HBV-related disease results from infections acquired in infancy through perinatal or early childhood exposure to HBV in Asia-Pacific. Hepatitis B during pregnancy presents unique management issues for both the mother and fetus. These APASL guidelines provide a comprehensive review and recommendations based on available evidence in the literature, for the management of females with HBV infection through every stage of pregnancy and postpartum. These also address the concerns, management challenges, and required follow-up of children born to hepatitis B-positive mothers.

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“…Abass 2001 [15] Retrospective 1999 Delhi 6910 70 ELISA -7 Sahni 2004 [16] Prospective 2001 -2002 Delhi 987 22 ELISA -8 Shenoy 2004 [17] Prospective 2001 Karnataka 300 12 Both 1 5…”

Section: Study Qualitymentioning

confidence: 99%

Seroprevalence of Hepatitis B Virus Among Pregnant Women in India: A Systematic Review and Meta-Analysis

Giri

Sahoo²,

Angadi³

et al. 2022

Journal of Clinical and Experimental Hepatology

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Controlling perinatally acquired hepatitis B

Cited by 6 publications

References 3 publications

Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India

Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India

Asian Pacific association for the study of liver (APASL) guidelines: hepatitis B virus in pregnancy

Seroprevalence of Hepatitis B Virus Among Pregnant Women in India: A Systematic Review and Meta-Analysis

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