The industrial impacts on the environment need to be minimized to reduce climate change, which will benefit human beings. Industry 4.0, the new production paradigm, promises productivity gains for companies that manage to implement it, but it is also dependent on natural resources, impacting the environment. The aim of this study is to identify and analyze possible cleaner production strategies associated with Industry 4.0 to optimize manufacturing systems in Industry 4.0 implementation projects, in addition to reducing the environmental impacts of these companies. Through a literature search, cleaner production strategies associated with Industry 4.0 were identified and classified into ten dimensions (strategy, waste, recycling, life cycle, resources, energy, production, work, performance and environment) contributing to the theory. The possibilities of using Industry 4.0 technologies were analyzed to meet each dimension. The relevance of this study lies in presenting possibilities for using and developing technologies and applications to meet these dimensions of cleaner production and helping those involved in Industry 4.0 projects to implement it more stably, contributing to the theory and practice.