2021
DOI: 10.3390/diagnostics11112155
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Controlling Droplet Marangoni Flows to Improve Microscopy-Based TB Diagnosis

Abstract: In developing countries, the most common diagnostic method for tuberculosis (TB) is microscopic examination sputum smears. Current assessment requires time-intensive inspection across the microscope slide area, and this contributes to its poor diagnostic sensitivity of ≈50%. Spatially concentrating TB bacteria in a smaller area is one potential approach to improve visual detection and potentially increase sensitivity. We hypothesized that a combination of magnetic concentration and induced droplet Marangoni fl… Show more

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Cited by 4 publications
(2 citation statements)
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“…Sputum smear microscopy has generally been considered the most effective approach for diagnosing lung diseases like TB. Specimens of sputum expectorated by patients with symptoms are placed chemically onto plain glass microscope slides [ 8 ]. Then, they are analyzed by laboratory procedures that identify acid-fast bacteria (AFB), like Mycobacterium TB cells [ 86 ].…”
Section: Imaging Modalitiesmentioning
confidence: 99%
See 1 more Smart Citation
“…Sputum smear microscopy has generally been considered the most effective approach for diagnosing lung diseases like TB. Specimens of sputum expectorated by patients with symptoms are placed chemically onto plain glass microscope slides [ 8 ]. Then, they are analyzed by laboratory procedures that identify acid-fast bacteria (AFB), like Mycobacterium TB cells [ 86 ].…”
Section: Imaging Modalitiesmentioning
confidence: 99%
“…It helps clinicians identify and pinpoint disease progressions more precisely. Numerous imaging modalities have been utilized to detect and analyze lung diseases, including chest X-rays [ 3 ], CT scans [ 6 ], MRI [ 7 ], PET [ 6 ], sputum smear microscopy images (SSMI) [ 8 ], and molecular imaging [ 9 ]. X-rays and CT scans are the most commonly used anatomic imaging modalities for detecting and diagnosing various lung diseases [ 6 ].…”
Section: Introductionmentioning
confidence: 99%