Controlled self-assembly of glycoprotein complex in snail mucus from lubricating liquid to elastic fiber

Zhong, Tianyi; Liu, Min; Wang, Zhiyuan; Zhang, Feng

doi:10.1039/c8ra01439f

Cited by 26 publications

(30 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A lyophilized mucus sample was hydrolyzed and purified with boiling hydrochloric acid, then the amino acid composition was determined using an amino acid analyzer (Hitachi L8900) [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Silver/Snail Mucous PVA Nanofibers: Electrospun Synthesis and Antibacterial and Wound Healing Activities

et al. 2022

View full text Add to dashboard Cite

Healthcare textiles are gaining great attention in the textile industry. Electrospun nanofibers are considered the golden soldiers due to their strength, flexibility, and eco-friendly properties. The present study aimed to evaluate the potency of polyvinyl alcohol (PVA) nanofibers loaded with newly biosynthesized silver nanoparticles (Ag-NPs) as a wound healing dressing. Chocolate-band snail (Eobania vermiculata) mucus (which is part of the Mollusca defense system) was used as a novel reducing and stabilizing agent. Data indicated the effectiveness of Eobania vermiculata’s mucus in silver nanoparticle synthesis after a 24 h incubation time. The biosynthesized AgNPs-SM showed a 13.15 nm particle size, −22.5 mV ζ potential, and 0.37 PDI, which proved the stability of the synthesized nanoparticles. Eobania vermiculata mucus and AgNPs-SM showed potent antibacterial activity, especially against Pseudomonas aeruginosa. The electrospinning technique was applied in the fabrication of PVA/AgNPs-SM nanofibers, which were homogenous with a fine diameter of about 100–170 nm and showed a significantly high antimicrobial activity. In vitro and in vivo studies revealed that PVA/AgNPs-SM nanofibers were safe and efficiently enhanced the wound healing process (typical histological picture of the proliferative phase with compact and well aligned collagen fibers in the dermal tissue after 12 days) together with bacterial growth inhibition in the infected skin area.

show abstract

“…A lyophilized mucus sample was hydrolyzed and purified with boiling hydrochloric acid, then the amino acid composition was determined using an amino acid analyzer (Hitachi L8900) [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Silver/Snail Mucous PVA Nanofibers: Electrospun Synthesis and Antibacterial and Wound Healing Activities

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In addition to the extremely strong adhesion, abalone can also leave the substrate and move around independently, in which case, the secreted mucus also plays an important role. A similar phenomenon is observed in terrestrial gastropods, such as snails and slugs [20][21][22][23][24][25]. Furthermore, Lin et al [26] used the atomic force microscope (AFM) to measure the adhesion force of a single seta distributed on the foot, and found that the main sources of microscopic adhesion are van der Waals force and capillary force.…”

mentioning

confidence: 59%

The co‐effect of microstructures and mucus on the adhesion of abalone from a mechanical perspective

et al. 2021

Biosurface and Biotribology

View full text Add to dashboard Cite

Reliable and reversible adhesion underwater is challenging due to the water molecules and weak layers of contaminants at the contact interface, which requires to deepen the understanding of wet adhesion of biological surfaces. Herein, the co-effect of microstructures and mucus of abalone foot on wet adhesion is investigated from both experimental and theoretical perspectives. The morphologies, adhesion force and coefficient of friction indicate that the mucus in adhesion zone is crucial for successful attachment of abalone based on capillary forces and viscous forces, and the mucus in non-adhesion zone with lower adhesion force and friction coefficient may behave as a lubricant for the locomotion. The theoretical calculation manifests that the microstructures may help abalone to form multiple liquid bridges with the secreted mucus, and significantly increase the wet adhesion force of abalone. These findings will bring profound views into the underlying mechanisms of biological surface adhesion.

show abstract

“…Denny (1981) also proposed that gastropods decrease the thickness of the mucus layer when crawling on a vertical surface. In fact, Zhong et al (2018) found that nanoparticle assembly during mucus production was altered to improve viscosity when moving across an inclined plate in order to overcome the influence of gravity. Although this does reduce slippage, it increases the force needed to move the individual forward, likely reducing speed.…”

Section: Discussionmentioning

confidence: 99%

How fast is a snail’s pace? The influences of size and substrate on gastropod speed of locomotion

Smith

Ruxton

2021

Journal of Zoology

View full text Add to dashboard Cite

Terrestrial gastropods display monotaxic direct crawling. During locomotion, smooth muscle contraction stimulates a series of pedal waves that move along the ventral surface of the foot. These waves interact with a thin layer of mucus produced by the foot, propelling the animal forward. Although the mechanism by which this process occurs has been well studied, less is known about how morphological or environmental factors affect this process, and ultimately how they may alter the speed of propulsion. In this study, we tested the influences of body size, substrate type, and substrate orientation on crawling speed in the terrestrial snail Cornu aspersum. We found that substrate texture and orientation had a strong effect on speed, whereas snail body size and the presence of a conspecific trail did not. Crawling speed across rough sandpaper was the most striking, showing a clear inversely proportional relationship between the size of abrasive particle and speed. We suggest that this may be the result of substrate attributes interfering with mucus adhesion or mucus production, subsequently affecting locomotion, although gait choice or the frequency and length of each pedal wave may also play a role.

show abstract

Controlled self-assembly of glycoprotein complex in snail mucus from lubricating liquid to elastic fiber

Abstract: Terrestrial snail could intelligently employ elastic fibers clinging itself onto the inverted smooth plate.

Cited by 26 publications

References 26 publications

Silver/Snail Mucous PVA Nanofibers: Electrospun Synthesis and Antibacterial and Wound Healing Activities

Silver/Snail Mucous PVA Nanofibers: Electrospun Synthesis and Antibacterial and Wound Healing Activities

The co‐effect of microstructures and mucus on the adhesion of abalone from a mechanical perspective

How fast is a snail’s pace? The influences of size and substrate on gastropod speed of locomotion

Contact Info

Product

Resources

About