volume 273, issue 1-2, P23-27 2004
DOI: 10.1016/j.ijpharm.2003.12.004
View full text

Abstract: The present study was carried out to evaluate the possibility of using the polymer EVA membrane as an EVA matrix system for transdermal delivery of atenolol. The effects of drug concentration, temperature, and plasticizers on drug release were studied from the atenolol-EVA matrix. The release rate of drug from the EVA matrix increased with increased temperature and drug loading doses. The flux of atenolol versus the reciprocal of the loading dose yielded a straight line. The release of atenolol from the EVA ma…

expand abstract