Controlled release of antifungal volatiles of thyme essential oil from β-cyclodextrin capsules

Solubility, photostability and antifungal activity of phenylpropanoids encapsulated in cyclodextrins

“…HPb-CD/trans-anethole showed the best inhibitory activity against F. oxysporum and HP-b-CD/eugenol against B. cinerea. Similar results were found in literature (Del Toro-Sanchez et al, 2010;Zhao, Wang, Yang, & Tao, 2010).…”

“…3). This increase could be probably attributed to the fact that HP-b-CD acts as a carbohydrate source for fungi (Del Toro-Sanchez et al, 2010) or encapsulates substances produced by fungi that self-inhibit the mycelium growth (López-Nicolás, Pérez-Gilabert, García-Carmona, Lozano-Carrillo, & Morte, 2013). We should note that the chemical structure of CDs (hydrophilic nature and bulk volume) do not allow them, neither their inclusion complexes, to permeate biological membranes (Loftsson et al, 2005).…”

Physicochemical and release characterisation of garlic oil-β-cyclodextrin inclusion complexes

“…Ayala-Zavala et al (2008) reported that the microcapsule yield at 12:88 (w/w) ratio of GO to b-CD was 94.58%, and the total volatile load was 20.24%. The driving forces between CDs and drugs which have been proposed to justify the complex formation are hydrogen bonds, van der Waals forces, hydrophobic interactions and the release of ''high-energy water'' molecules from the cavity (Salústio, Feio, Figueirinhas, Pinto, & Marques, 2009). Del Toro-Sánchez et al (2010 reported that hydrogen bonds and hydrophobic interactions were detected between the thyme essential oil constituent and b-CD by IR and 1H NMR spectroscopy.…”

Short Overview of Encapsulation Technologies for Delivery of Bioactives to Food

“…Encapsulation in CDs has number of advantages, but probably the most important one is that it enhances the solubility of poorly water-soluble bioactives [56,58,59,60], in that way making them more suitable for the applications in food industry. In addition to that, it was proved that β -CDs enable controlled release of encapsulated compounds [57,61,62].…”