Controlled host:guest ratio in an inclusion compound

Inclusion Compounds of Binaphthol with Lutidines − Structures, Selectivity and Kinetics of Desolvation

“…The E a values obtained here fall in the small range 80Ϫ110 kJ mol Ϫ1 , similar to those observed for other channel-type inclusion compounds with the same host BNP. [12,20] …”

Inclusion compounds of hydroxynaphthoic acids: co-crystal vs. salt formation

“…We note that in the structures formed between 2,2 0 -dihydroxy-1,1 0 -binaphthyl and 1,4-dioxane, 23 the compound with a guest : host (G : H) ratio of 3.5 has the 1,4-dioxane located in channels and yields an activation energy of desolvation of 61 kJ mol À1 while the inclusion compound with G : H ratio of 1.5 had an activation energy of 86 kJ mol À1 . The host 9,9 0 -(biphenyl-4,4 0 -diyl)bis(fluoren-9-ol) forms an inclusion compound with dioxane with G : H ratio of 3 which decays in a single step with E a ¼ 95.5 kJ mol À1 and the dioxane molecules are in restricted channels.…”

Control of Differential Inclusion Complexation in the Solid State by Seed Crystals

“…Crystal data for 1·(Et 2 O) 2 (2): C 28 H 34 O 4 , M r = 434.55, monoclinic, b = 108.86(2)8, a = 11.659 (7), b = 9.757(6), c = 11.886 (7) , V = 1279.4(13) 3 , T = 293 K, space group Pn, Z = 2, l(Cu Ka ) = 1.54 ; for 1835 observed reflections, the final R (on F) = 0.0798 and wR (on F 2 ) = 0.2306 for I > 2s(I).…”

“…However, the crystal structure of a 1:2 complex of 1 with 2-cyclohexenone is completely different to that of 2, and the structures of 2:3 complexes of 1 with THF and 1,4-dioxane are also different. [7] These data suggest that a crystal of an inclusion complex is effective as a pseudo seed crystal for the formation of a complex at the same host/guest ratio but with a different guest compound ( Table 2). For example, contact of powdered 1 with gaseous EtOAc for 3 h in the presence of seed crystal (1) 3 ·MeOAc gave the complex (1) 3 ·EtOAc, also in a 3:1 host/ guest ratio.…”