“…[1][2][3] Recently, an integration of nanoparticles with chirality (an asymmetric property by which an object is non-superposable on its mirror image) enables the formation of chiral nanoparticles (or CNPs) that have optical activity, denoting differential interactions with left-and right-handed (or LH and RH) circularly polarized light (CPL). [4] Producing CNPs unavoidably requires chiral stimulation from, e.g., chiral ligands, [5][6][7][8] chiral templates, [9][10][11] CPL, [12,13] helical magnetic fields, [14] orbital angular momentum, [15] macroscopic asymmetric gradients of biaxial strain fields, [16,17] and macroscopic shear forces. [18,19] An addition of chirality provides CNPs with various promising functions, such as ultrasensitive molecular detection and bioanalysis, [20][21][22] enhanced enantiodifferentiation, [23][24][25][26] active nanorheology, [27] polarization-dependent display, [14,28] enantioselective photocatalysis [29] and synthesis, [30][31][32] and enantiospecific bioapplications.…”