“…Although the application of optimal control in biomedical engineering has been around since 1980s 5–7, recently, there is a renewed and intense interest in this area 8–10. There are a number applications of optimal control in biomedical sciences, such as blood glucose control in diabetes 11, 12, anesthesia 13, management of thyroid 14, administration of drugs 7, cancer therapy 7, 15–17, circulatory systems 18, human immunodeficiency virus (HIV) 19, prosthetics 20, 21, predator–prey problem 22, 23, and epidemics problem 22, 23.…”