Control of the retention selectivity of rare earth octaethylporphyrins in reversed-phase high-performance liquid chromatography using amines as mobile phase additives

Lanthanide complexes exhibit interesting spectroscopic properties yielding many applications as imaging probes, natural chirality amplifiers, and therapeutic agents. However, many properties are not fully understood yet. Therefore, we applied magnetic circular dichroism (MCD) spectroscopy, which provides enhanced information about the underlying electronic structure to a series of lanthanide compounds. The metals in the M(3+) state included Y, La, Eu, Tb, Dy, Ho, Er, Tm, Yb, and Lu; the spectra were collected for selected tetraphenylporphin (TPP) and octaethylporphin (OEP) complexes in chloroform. While the MCD and UV-VIS absorption spectra were dominated by the porphyrin signal, metal binding significantly modulated them. MCD spectroscopy was found to be better suited to discriminate between various species than absorption spectroscopy alone. The main features and trends in the lanthanide series observed in MCD and absorption spectra of the complexes could be interpreted at the Density Functional Theory (DFT) level, with effective core potentials on metal nuclei. The sum over state (SOS) method was used for simulation of the MCD intensities. The combination of the spectroscopy and quantum-chemical computations is important for understanding the interactions of the metals with the organic compounds.

show abstract

“…We used TPP and OEP lanthanide acetylacetonate (acac) complexes prepared and described previously 10,11,31 (Fig. 1).…”

Section: Measurementsmentioning

confidence: 99%

Magnetic Circular Dichroism of Porphyrin Lanthanide M³⁺ Complexes

et al. 2014

View full text Add to dashboard Cite

show abstract

Behavior of new complexes of tetrakis(4‐methoxyl phenyl)porphyrin with heavy rare earth elements in reversed‐phase high performance liquid chromatography

Zhang

Wang

Hou

et al. 2004

J of Separation Science

View full text Add to dashboard Cite

An HPLC method has been developed for the separation of new complexes of tetrakis(4-methoxylphenyl)porphyrin (TMOPP) with four heavy rare earth elements (RE = Y, Er, Tm, and Yb). The function of amine and acid in the mobile phase has been investigated and a reasonable explanation is presented. Successful separation of the RE-TMOPP-Cl complexes is accomplished in 10 min with a mobile phase consisting of methanol-water-acetic acid-triethanolamine. The detection limits (S/N= 3) for the four complexes are 0.01 microg/mL. This method is rapid, sensitive, and simple.

show abstract

Porphyrins as ligands for trace metal analysis by high-performance liquid chromatography

Shi

1997

Talanta

View full text Add to dashboard Cite

Control of the retention selectivity of rare earth octaethylporphyrins in reversed-phase high-performance liquid chromatography using amines as mobile phase additives

Cited by 7 publications

References 15 publications

Magnetic Circular Dichroism of Porphyrin Lanthanide M³⁺ Complexes

Magnetic Circular Dichroism of Porphyrin Lanthanide M³⁺ Complexes

Behavior of new complexes of tetrakis(4‐methoxyl phenyl)porphyrin with heavy rare earth elements in reversed‐phase high performance liquid chromatography

Porphyrins as ligands for trace metal analysis by high-performance liquid chromatography

Contact Info

Product

Resources

About

Control of the retention selectivity of rare earth octaethylporphyrins in reversed-phase high-performance liquid chromatography using amines as mobile phase additives

Cited by 7 publications

References 15 publications

Magnetic Circular Dichroism of Porphyrin Lanthanide M3+ Complexes

Magnetic Circular Dichroism of Porphyrin Lanthanide M3+ Complexes

Behavior of new complexes of tetrakis(4‐methoxyl phenyl)porphyrin with heavy rare earth elements in reversed‐phase high performance liquid chromatography

Porphyrins as ligands for trace metal analysis by high-performance liquid chromatography

Contact Info

Product

Resources

About

Magnetic Circular Dichroism of Porphyrin Lanthanide M³⁺ Complexes

Magnetic Circular Dichroism of Porphyrin Lanthanide M³⁺ Complexes