Control of Hiccup by Inhalation of Carbon Dioxide

Sheldon, Russell F.

doi:10.1001/jama.1927.02690140014004

Cited by 8 publications

(2 citation statements)

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“…On the other hand, in certain conditions of overexcitability a decrease in ventilation appears to be beneficial. For instance, by rebreathing Fitz (35) was able to cure muscular cramp, Sheldon (130) to control hiccough, and Lennox and Cobb (67,68) to reduce the frequency of epileptic seizures in some patients. Lennox and Cobb, Foerster (36), Grant and Goldman (43) and others have been able in many cases to do the reverse and induce epileptic seizures by overventilation.…”

Section: Oxygen and Carbon Dioxidementioning

confidence: 99%

Psychological effects of drugs.

Darrow¹

1929

Psychological Bulletin

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The reader is referred to previous reviews by Poffenberger (109),. Meyer (94), Robinson (119) and Darrow (18). ALCOHOL Evidence in the preceding reviews indicated that alcohol tends toimpair all levels of performance and that the alleged progressive deterioration, first of higher and later of lower functions, is probably a misinterpretation of the facts. Present material, with some exceptions, supports this opinion. The apparent excitation sometimes noted at "lower" or mechanical levels may be attributed (1) toreflex effects from irritation of the oral and gastric mucous membranes and (2) to a partial narcosis of the higher controlling and inhibitory nervous centers, thereby giving greater freedom to lower mechanisms actually under the same degree of narcosis.As regards excitation by alcohol Cushny (14) and Weeks (151) offer as the consensus of medical opinion the belief that the chief effects are from the irritation of the mucous membranes of the alimentary tract. Recently Takahashi (142) found that the application of alcohol to the mucosa caused initial vasoconstriction with a rise in blood pressure. This tended to be followed, especially after larger quantities, by depression of the vasomotor center and a fall in blood pressure. Cushny, summarising circulatory findings, reportsvarying blood pressure changes following small amounts of alcohol, but primarily depression after large amounts. Any acceleration of the pulse he attributes to the increased muscular activity generally characteristic of " excited " states. Weeks notes that when reflex

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Section: Oxygen and Carbon Dioxidementioning

confidence: 99%

Psychological effects of drugs.

Darrow¹

1929

Psychological Bulletin

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“…3 Inducing hypercapnia as therapy for hiccups was suggested and tried by a number of practitioners, such as the Americans Russel Firth Sheldon (1885Sheldon ( -1960 and Brian Collins Sword in Boston in the late 1920s and later by Hamilton Bailey (1894Bailey ( -1961 at the Royal Northern Hospital in London. 4,5 Their pioneering work deserves to be mentioned.…”

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confidence: 99%