Control of Heart Rate in Infant and Child Tachyarrhythmia With Reduced Cardiac Function Using Landiolol (HEARTFUL)　― Results of a Prospective, Multicenter, Uncontrolled Clinical Study ―

Abstract

macological therapy, non-pharmacological treatments, such as catheter ablation or implantation of a cardioverter defibrillator, are an option for adult patients. 3,4 However, non-pharmacological approaches are sometimes difficult in some types of CHD, or after surgical procedures for anatomical reasons in children. 2,5 Amiodarone and nifeka-V arious tachyarrhythmias may occur after surgical repair of congenital heart disease (CHD) and they may be potentially fatal. 1,2 Following onset, emergency therapy to control and terminate the tachycardia, and to prevent circulatory deteriorations, is usually mandatory. In patients with tachyarrhythmia resistant to phar-

Antiarrhythmic Drug Dosing in Children—Review of the Literature

“…Landiolol's half-life is reported to be up to 4 min, with an onset of action reported within 1 min following iv administration. Landiolol may cause arterial hypotension, bradycardia, dizziness, or headache, among others [58][59][60][61][62].…”