Control of dispersity in stereoselective telomerizations: the addition/cyclization/transfer strategy

Template Controlled Oligomerizations

“…Only methyl acrylate polymerization was arrested by template 64 to provide the macrocyclized product 96 in modest yield as a mixture of five diastereomers (Scheme [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Vinyl acetate and acrylonitrile led only to uncontrolled polymerization, while vinylene carbonate did not react under the standard experimental conditions.…”

“…This curious observation refocuses concerns about yield loss to a critical choice that a template-bound pMMA radical 99 faces: macrocyclization to afford the controlled-8 Temdate Controlled Olipomerizations length oligomer 94 vs. addition of a fourth monomer to lead ultimately to 100 (Scheme [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. 10% of unreacted template was recovered.…”

Recent Reviews

“…Acid derivatives, book, 166 Acidities, equilibrium, 10 Addition reactions, free radical, 62 Air-water interface, molecular recognition at, 24 Aldose reductase inhibitors, 132 Alkaloids, aUelochemical properties, 138 amaryllidaceae and sceletium, 70 amphibian, 140 mammalian, 139 marine, 40 Alkanes, electrophilic activation, 2 Alkylidene carbenoids, 37 Alkylidyne ligands, 19 Alkyls, Group 13,48 Allelochemical properties, of alkaloids, 138 Aliene cycloaddition, intramolecular, 154 Amaryllidaceae and sceletium, 70 Amino acid esters, cleavage, 65 Amino acid racemization, 57 Amino acid sequence, 39 Amino acids, complexes of, 87 fluorine-containing, 107 phosphorus-containing, 107 Index Ammonium halides, in the vapor phase, 50 Amphibian alkaloids, 140 Angiotensin-II, receptor antagonists, nonpeptide, 131 Anion receptors, design, 99 Annulation, 45 Anthracycline antibiotics, 51 Anti-Michael intramolecular additions, 111 Antibiotics, anthracycline, 51 enediyne, synthesis, 94 Antibody catalysis, 3,4,53 Antitumor agents, DNA-alkylating, 129 synthesis, 97 Aqueous media, reactions in, 42 Arene chromium tricarbonyl, carbocations, 110 catalysts, 116 Arene cis-diols, in synthesis, 137 Aromatic reactivity, 119 Asymmetric catalysis, 56 chiral ligands in, 63 Asymmetric reactions, 43 with titanium reagents, 136 Asymmetric synthesis, 126 book, 160 catalytic, book, 164 of amino acids, 107 of macrocyclic ligands, 100 with jV-sulfonyloxaziridines, 82 Asymmetry, fragile, 85 Azadienes, 12 Azaparacyclophanes, cage-type, 78 Baldwin's rules, 8…”