Control of Cattle Grubs by Pour-On, Injection, and Spray1

Kohler, Paul H.; Rogoff, Wm. M.

doi:10.1093/jee/55.4.539

Cited by 3 publications

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“…It is an anthelmintic agent with activity against a wide range of gastrointestinal nematodes of ruminants (Drudge and Szanto, 1963;Wood et al, 1961). The compound is highly effective against the cattle grub (hypoderma) when fed (Drummond, 1963c), injected intramuscularly (Drummond, 1963b;1963c), or following pour-on and oral drench treatments (Kohler and Rogoff, 1962;Neel etal., 1963). The insecticide also shows promise in the control of certain fleas (Hill et al, 1963) and hornflies (Drummond, 1963a).…”

mentioning

confidence: 99%

Absorption, Metabolism, and Excretion of Tritium-Labeled Famphur in the Sheep and Calf

Gatterdam¹,

Woźniak²,

Bullock³

et al. 1967

J. Agric. Food Chem.

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The metabolism of famphur, 0,0-dimethyl , -(lV,Ar-dimethylsulfamoyl)phenyl phosphorothioate, in the sheep and calf involves rupture of P-Omethyl, P--phenyl, and TV-methyl bonds to yield water-soluble metabolites which are eliminated in the urine. Phenolic metabolites are excreted primarily as glucuronide derivatives. Marked differences in metabolism and excretion patterns occur depending on the method of administration, intramuscular injection providing more sustained famphur levels, and lower famoxon levels in blood than intravenous administration.

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confidence: 99%