Control of carbendazim toxicity using banana peel powder in rats

Abdel-Rahman, Gomaa N.; Fouzy, A. S. M.; Amer, Mahmoud; Saleh, Essam M.; Hamed, Islam A.; Sabry, Bassem A.

doi:10.1016/j.btre.2022.e00773

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Various plants and their oils have been previously used to treat the toxicity of CBZ on animals, such as olive ( Olea europaea) leaves Zari and Al-Attar, (2011) , licorice ( Glycyrrhiza glabra ), Fenugreek ( Trigonella foenum-graecum Linn .) seeds extract Lamfon (2012) , Gingo bilola extract Mahboub and Lamfon, (2013) , Ginger ( Zingiber officinale ) Salihu et al (2016) , Jaft internal layer of Quercus brantii Mirzaei et al (2015) , Nigella sativa oil Hashem et al (2018) , Quercetin Abou Zaid et al (2018) , Nigella sativa and Foeniculum vulgar seeds extracts Alghamdi, (2020) , Vitamin C ( Lalhriatpuia et al, 2021 , Kiran, 2022 ), and banana peel ( Abdel-Rahman et al, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L. oil on testes of male rats: Physiological, histological and in silico study

Hashim,

Al-Attar,

Alomar

et al. 2024

Saudi Journal of Biological Sciences

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Section: Discussionmentioning

confidence: 99%

Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L. oil on testes of male rats: Physiological, histological and in silico study

Hashim,

Al-Attar,

Alomar

et al. 2024

Saudi Journal of Biological Sciences

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Mitigation of Hepatotoxicity via Boosting Antioxidants and Reducing Oxidative Stress and Inflammation in Carbendazim-Treated Rats Using Adiantum Capillus-Veneris L. Extract

et al. 2023

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Exposure to food contaminants continues to be a substantial source of human health risks all over the world, particularly in developing countries. Carbendazim (CBZ) is a chemical fungicide used to control the spread of various fungi and other pathogens in the agriculture and veterinary sectors. The hazardous effects of CBZ on human health occur due to the accumulation of its residues in agricultural food products. In this study, the possible hepatoprotective effects of Adiantum capillus-veneris L. (ACVL) extract were evaluated in CBZ-treated rats. A GC-MS analysis revealed that ACVL extract contained several bioactive hydrocarbon components and fatty acids, and that the components exerted hepatic protection by mitigating oxidative stress via upregulating antioxidant agents and neutralizing nitrogen and oxygen free radicals. Moreover, ACVL extracts relieved hepatic inflammation via decreasing NO, NF-κB, and pro-inflammatory cytokines (TNF-a, IL-6) in the liver of CBZ-treated rats, both at protein and mRNA levels. In addition, the protective effect of ACVL has appeared in the histopathological figures and function markers in the livers of CBZ-treated rats. According to the present results, ACVL extract can protect the hepatic tissue and restore its functions to a control level in CBZ-treated rats; this effect may be attributed to its antioxidant and anti-inflammatory activities.

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Control of carbendazim toxicity using banana peel powder in rats

Cited by 2 publications

References 33 publications

Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L. oil on testes of male rats: Physiological, histological and in silico study

Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L. oil on testes of male rats: Physiological, histological and in silico study

Mitigation of Hepatotoxicity via Boosting Antioxidants and Reducing Oxidative Stress and Inflammation in Carbendazim-Treated Rats Using Adiantum Capillus-Veneris L. Extract

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