Control groups for HIV prevention efficacy trials: what does the future hold?
Holly Janes,
Susan Buchbinder
Abstract:Purpose of review
Ending the HIV epidemic will require the development of additional effective immune-mediated and nonimmune-mediated means of HIV prevention. Evaluating novel interventions requires large, controlled trials demonstrating efficacy. Recent advances in the field of HIV prevention necessitate new approaches to efficacy trial design.
Recent findings
Three classes of efficacy trial designs are possible: standard of prevention-controlled trial… Show more
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