Contribution of UVA irradiance to the erythema and photoaging effects in solar and sunbed exposures

Solá, Yolanda; Lorente, J.

doi:10.1016/j.jphotobiol.2014.10.024

Cited by 25 publications

(19 citation statements)

References 35 publications

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“…UVB phototherapy, under medical supervision. However, sunbeds with higher (>1.5%) UVB levels have been manufactured to speed up the tanning process, and they belong to the CIE type 4 as far as the effective UVB output is calculated …”

Section: Sunbedsmentioning

confidence: 99%

“…7,8 These lamps usually have mean unweighted UVB irradiances lower than that provided from natural summer sun (at latitudes from 37°S to 35°N). 8 However, the UVB content is often greater than 0.8%, and therefore, the contribution of UVB to the overall DNA damage and erythematogenic effect is biologically predominant on that of UVA. 9 In addition, when the fluorescent lamps age through prolonged operation, their emission spectrum shifts towards a higher UVB content.…”

Section: Sunbedsmentioning

confidence: 99%

“…64 In comparison to natural sunlight, it has been calculated that the photoageing effect of 1 MED from UVA sunbeds is 2-4 times larger than that of the same physical solar dose. 8,9 In addition, UVA1 tanning does not prevent further collagenolytic changes from environmental exposures in lightly pigmented individuals. 65…”

Section: Cutaneous Malignant Melanoma (Cmm)mentioning

confidence: 99%

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Sunbeds and carcinogenesis: the need for new regulations and restrictions in Europe from the Euromelanoma perspective

Calzavara-Pinton

Arisi

Wolf

2019

Acad Dermatol Venereol

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Experimental investigations have definitely assessed that ultraviolet A (UVA) as well as ultraviolet B (UVB) radiation induce mutagenic DNA photoproducts and other cell damages with a carcinogenic potential. Artificial tanning increases significantly the lifetime risk for basal cell carcinoma, squamous cell carcinoma and melanoma particularly in subjects with fair skin type, subjects with a history of skin cancer or frequent childhood sunburn or if exposures took place at an age younger than 18 years. In addition, experimental and clinical evidence indicate that UVA exposure promotes skin photoageing. Therefore we are dealing with a recreational activity (for customers) and a profitable business (for the tanning industry) with human costs, i.e. an increase in morbidity and mortality by skin cancer, and health and social costs leading to an increased expenditure by the European national health systems. In a few European countries, legislation has recently prohibited the use of sunbeds for minors, pregnant women, people with skin cancer or a history of skin cancer and individuals who do not tan or who burn easily from sun exposure. However, this legislation seems to be insufficient from a photobiological perspective, and importantly, it is largely disregarded by consumers and tanning industry. Therefore the Euromelanoma group proposes a new, more stringent regulation for the tanning industry and restrictions for customers, particularly for those individuals with constitutional and anamnestic risk factors. Finally, we ask for an enhanced commitment to increase the awareness of the general population on the risk of artificial tanning.

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Section: Sunbedsmentioning

confidence: 99%

Section: Sunbedsmentioning

confidence: 99%

Section: Cutaneous Malignant Melanoma (Cmm)mentioning

confidence: 99%

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Sunbeds and carcinogenesis: the need for new regulations and restrictions in Europe from the Euromelanoma perspective

Calzavara-Pinton

Arisi

Wolf

2019

Acad Dermatol Venereol

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“…Por ser capaz de atingir camadas mais profundas da derme (derme reticular) a radiação UVA pode ser mais responsável por este efeito. 31 Vários estudos epidemiológicos indicam que a PUVAterapia induz oncogénese cutânea. Acima dos 200 tratamentos (ou dose cumulativa máxima de 1000-1500J/cm 2 ) parece haver um aumento de 10 vezes do risco de carcinoma espinocelular e, por isso, não deve ser ultrapassado este limiar.…”

Section: Efeitos Adversos Crónicosunclassified

Protocolos de Fototerapia no Tratamento da Psoríase

Teixeira

Filipe²

2016

SPDV

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RESUMO -A psoríase é uma doença inflamatória crónica muito frequente na prática Dermatológica. Apesar de ser possível o controlo da maioria dos doentes com recurso apenas a terapêuticas tópicas, uma percentagem significativa é refractária a estes tratamentos, sendo necessária a instituição de terapêutica sistémica. Nestes casos, uma das opções será a fototerapia. Neste trabalho são detalhadas as várias modalidades terapêuticas da Fototerapia disponíveis no tratamento da Psoríase e os protocolos mais frequentemente utilizados. PALAVRAS-CHAVE -Fototerapia; Psoríase. Phototherapy Protocols used in the Treatment of Psoriasis ABSTRACT -Psoriasis is a chronic inflammatory disease frequently seen in dermatologic practice. Although it is possible to control the majority of patients using only topical therapies, a significant percentage is refractory to these treatments, requiring systemic therapies. In these cases, one of the possible options is phototherapy. This paper details the various available therapeutic modalities of phototherapy in the treatment of psoriasis and the most frequently used protocols. KEY-WORDS -Phototherapy; Psoriasis.INTRODUÇÃO A psoríase é uma doença inflamatória crónica, relativamente frequente, variando a sua incidência mundial entre 0,45-4,6%. Apesar de a maioria dos doentes ser controlada com terapêuticas tópicas, cerca de 20% dos doentes têm doença moderada-grave, definida como atingimento superior a 5% da área corporal total, ou Psoriais Area Severity Index (PASI) superior a 7-12, ou Dermatology Life Quality Index (DLQI) superior a 10, sendo frequentemente refractá-rios às terapêuticas tópicas convencionais.1 Apesar dos avanços consideráveis no conhecimento da imunopatogénese da psoríase e da introdução de agentes biotecnológicos e de pequenas moléculas que têm acção mais direccionada aos mecanismos da doença, as fototerapias continuam a ter um papel fundamental na estratégia terapêutica anti-psoriática. Nestes doentes, a fototerapia pode ser uma opção de primeira linha, promovendo reduções de 75% no PASI em mais de 75% dos doentes, após 4-6 semanas de tratamento.2 Para a obtenção do efeito terapêutico máximo, a fototerapia deve ser individualizada à fase da doença e ao doente em questão. Para tal, é mandatório que o clínico esteja familiarizado com as várias modalidades terapêuticas disponíveis, os seus mecanismos de acção e os diferentes protocolos terapêuticos. MODALIDADES TERAPÊUTICAS 1. PUVATERAPIAA PUVAterapia consiste na exposição à radiação UVA (320-400nm) em associação à administração sistémica ou tó-pica de um fotossensibilizante da família dos psoralenos. Os psoralenos pertencem a um grupo de compostos designados por furocumarinas, cuja estrutura química e posologia oral estão representadas no Tabela 1.3 O 8-metoxipsoraleno (8-MOP) é a molécula mais utilizada quer na PUVAterapia oral, quer na PUVAterapia tópica.

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“…UV is divided into ultraviolet A (UVA) (315-400 nm) and ultraviolet B (UVB) (280-315 nm), which reach the earth surface, and ultraviolet C (UVC) (200-280 nm), which is mostly 2 of 13 absorbed in the ozone layer and cannot reach the surface. UVA penetrates deeper into the dermal layer of the skin and produces reactive oxygen species that cause skin aging and wrinkle formation [5,6]. Meanwhile, UVB causes skin pigmentation, weakens skin barriers, and promotes erythema and skin cancer [7,8].…”

Section: Introductionmentioning

confidence: 99%

Development of UVB LED Lighting System Based on UV Dose Calculation Algorithm to Meet Individual Daily UV Dose

Park

Lim

2019

Applied Sciences

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Ultraviolet B (UVB) in sunlight is known to promote health when humans are exposed to optimum sunlight. Proper exposure to ultraviolet B is essential to produce vitamin D in the body, which is a particularly important factor for health. However, there has been an increase recently in the number of people who are lacking sunlight exposure due to staying indoors. Avoiding ultraviolet (UV) rays leads to health deterioration. To solve this problem, a portable ultraviolet measuring device that provides users with the UV intensity information of outdoor sunlight has been developed while UVB Light Emitting Diode (LED) lighting technologies capable of providing UVB radiation have been studied. However, existing technologies are mere methods for providing information on ultraviolet rays and artificially exposing to ultraviolet rays, and there is a risk for the UV radiation amount to not meet the daily required UV dose. Therefore, in this paper, a UVB LED general lighting system based on a UV exposure calculation algorithm that supports users’ daily required UV dose is proposed. The proposed system is composed of an IoT (Internet of Things) UV measuring device that measures the UV dose indoors, as well as outdoors, UVB LED general lighting which can safely provide UVB doses at indoors, and a smartphone which provides information on the cumulative UV dose and the estimated amount of vitamin D while it controls UVB LED general lighting. In addition, it is possible to support users’ vitamin D synthesis by providing as much UV light as its shortage through UVB LED general lighting, based on an individual’s UV exposure amount through outdoor sunlight, using a smartphone implementing a UV dose calculation algorithm. In order to confirm the performance of the proposed system, a simulation was conducted assuming that users with skin types 2 and 3 performed outdoor activities within 30 min and entered the room. The result confirmed that the proposed lighting can provide users of all ages with the UV dose required per day.

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Contribution of UVA irradiance to the erythema and photoaging effects in solar and sunbed exposures

Cited by 25 publications

References 35 publications

Sunbeds and carcinogenesis: the need for new regulations and restrictions in Europe from the Euromelanoma perspective

Sunbeds and carcinogenesis: the need for new regulations and restrictions in Europe from the Euromelanoma perspective

Protocolos de Fototerapia no Tratamento da Psoríase

Development of UVB LED Lighting System Based on UV Dose Calculation Algorithm to Meet Individual Daily UV Dose

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