Contribution of six risk factors to achieving the 25×25 non-communicable disease mortality reduction target: a modelling study

Kontis, Vasilis; Mathers, Colin; Rehm, Jürgen; Stevens, Gretchen A; Shield, Kevin D.; Bonita, Ruth; Riley, Leanne M; Poznyak, Vladimir; Beaglehole, Robert; Ezzati, Majid

doi:10.1016/s0140-6736(14)60616-4

Cited by 370 publications

(326 citation statements)

References 62 publications

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“…Os principais fatores de risco que estão associados a estas doenças são hipertensão arterial, tabagismo, uso de álcool, inatividade física, dieta inadequada, obesidade e hipercolesterolemia. 2 Cerca de 80% das mortes por DCNT ocorrem em países de baixa ou média renda, onde 29% são de pessoas com menos de 60 anos, enquanto nos países de renda alta apenas 13% são mortes precoces.…”

Section: Introductionunclassified

Doenças Crônicas Não Transmissíveis: perfil da mortalidade no município de Natal/RN no período de 2000 a 2014

Marques

Amador

Nunes

et al. 2017

Rev Epidemiol Control Infect

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Justificativa e objetivos: Como consequência da transição demográfica e epidemiológica, atualmente as Doenças Crônicas não Transmissíveis (DCNT) são responsáveis pela maior carga de morbidade e mortalidade no mundo, evidenciando a necessidade de monitorar sua ocorrência. O objetivo desse estudo foi analisar a tendência temporal e descrever o perfil da mortalidade por DCNT no município de Natal-RN. Métodos: Foram analisados os óbitos ocorridos no período de 2000 a 2014, oriundos decorrentes das Neoplasias, Doenças do Aparelho Circulatório, Doenças do Aparelho Respiratório e Diabetes Mellitus. A partir dos dados do VIGITEL foram avaliados os principais fatores associados a estas causas. A tendência foi analisada pelo método de regressão linear simples. Resultados: Foram registrados 34.618 óbitos por DCNT, 49% do sexo masculino e 51% do feminino; as Neoplasias foram responsáveis por 32,4% dos óbitos; as Doenças do Aparelho Circulatório por 49,8%; as Doenças do Aparelho Respiratório por 6,9% e o Diabetes Mellitus por 10,9% dos óbitos. Foi observada tendência de redução da mortalidade pelo conjunto dessas causas; A população acima de 50 anos foi responsável por 88% dos óbitos. Houve redução na prevalência do Tabagismo e sedentarismo, porém aumento de sobrepeso e obesidade. Conclusões: As DCNT representam uma importante causa de morte em indivíduos acima de 50 anos no município de Natal, destacando-se as taxas de mortalidade por Diabetes em mulheres. DESCRITORES: Mortalidade. Doença Crônica. Vigilância Epidemiológica.

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Section: Introductionunclassified

Doenças Crônicas Não Transmissíveis: perfil da mortalidade no município de Natal/RN no período de 2000 a 2014

Marques

Amador

Nunes

et al. 2017

Rev Epidemiol Control Infect

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“…24,25 Estudios realizados a nivel mundial y regional muestran que alcanzar la meta de reducción de 30% del consumo de tabaco es un elemento clave para alcanzar un descenso de 25% en la mortalidad prematura debida a ENT para el año 2025, y que una meta más ambiciosa de un descenso de 50% en el consumo de tabaco aseguraría el alcance de esta meta en todas las regiones de la OMS. 26,27 El reto es claramente mayor si se toma en cuenta que este análisis sólo incluye un grupo seleccionado de las medidas del CMCT y que para combatir efectivamente la epidemia de tabaquismo es necesario que las Partes apliquen en forma progresiva la totalidad de las medidas del CMCT. Asimismo, las ratificaciones del Protocolo para la eliminación del comercio ilícito de los productos de tabaco tienen un ritmo más lento que el CMCT y, aun cuando fue adoptado en 2012, no está en vigor.…”

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Diez años del Convenio Marco de la OMS para el Control del Tabaco: avances en las Américas

Blanco¹,

Sandoval²,

Martínez-López³

et al. 2017

Salud Publica Mex

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“…As a result, the World Health Organization (WHO) and Global Cardiovascular Disease Taskforce disseminated information and approaches to reach the WHO 2025 targets, where control of risk factors plays a pivotal role. 4 Considering the above, it is clear that global and local investigation and monitoring of secular trends in cardiovascular (CV) morbidity and its related outcomes are one of the cornerstones for developing evidence-based, cost-effective, and region-and country-specific prevention programs.…”

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confidence: 99%

“…However, if the specific globally agreed targets on smoking, alcohol use, salt intake, obesity, and elevated blood pressure and glucose levels are achieved, the decline would approximate 34% and additional 37 million deaths will be delayed or prevented. 4 In conclusion, CVDs are a leading cause of morbidity and mortality worldwide. Control of modifiable risk factors and therapeutic developments throughout the last decades have resulted in improved overall outcomes of CV patients.…”

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confidence: 99%

Less is more: the dynamic epidemiology of cardiovascular diseases

Plakht¹,

Shiyovich²

2016

Polish Archives of Internal Medicine

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839the results of data regarding the characteristics and outcomes of about half million CV patients between 2006 and 2014 in Poland, is both interesting and important. The main findings of the latter study include the following temporal trends: 1) no significant change in the annual number of hospital admissions for CVD; 2) a shorter length of in-hospital stay for CVD admissions; 3) a decrease in the overall readmission rate; and 4) stable, with some tendency towards a decrease, in-hospital and 12-month adjusted mortality rates. The authors suggested that these findings could possibly result from better access to cardiology services, improvement in diagnostic and therapeutic measures, and in primary and secondary prevention. These findings are consistent with and largely confirm recent reports from other countries.A significant limitation of this work is the absence of evaluation and report of temporal trends in patients' characteristics, especially CV risk factors and major comorbidity, and the potential effect of such changes on investigated outcomes. This limitation is major because, as previously mentioned, changes in risk factors are a significant driving force behind changes in CVD morbidity and mortality and a focus for intervention. 5,6A recent analysis of 79 modifiable risks divided into 3 broad groups of behavioral, environmental and occupational, and metabolic risk factors in 188 countries showed that together they accounted for 88.5% of global CVD deaths and nearly 88% of global CV DALYs. 6 Although data on trends in important CV risk factors are much more limited than on mortality or some of the other CV outcomes and are rarely based on population-based studies, 5 several prominently observed changes should be mentioned. First and foremost, life expectancy is rising and population is getting older in most countries. This results in CV patients with an increased prevalence of CV risk factors and comorbidity, hence greatly Noncommunicable diseases (NCD) have surpassed communicable disease as the world's major disease burden. 1,2 The leading causes of NCD, accounting for approximately half of the annual deaths, are cardiovascular diseases (CVDs) with 17.9 million mortalities throughout 2015. 3 Furthermore, globally, the top 2 causes of years of life loss and disability-adjusted life years (DALYs) are ischemic heart disease (IHD) and stroke (ischemic and hemorrhagic). 2,3 Following the latter trends, in 2011, the UN General Assembly adopted a declaration that set a target, for all nations, to reduce the risk of premature death from NCDs by 25% by the year 2025 (known as 25 by 25). As a result, the World Health Organization (WHO) and Global Cardiovascular Disease Taskforce disseminated information and approaches to reach the WHO 2025 targets, where control of risk factors plays a pivotal role. 4Considering the above, it is clear that global and local investigation and monitoring of secular trends in cardiovascular (CV) morbidity and its related outcomes are one of the cornerstones for developing evidence...

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Contribution of six risk factors to achieving the 25×25 non-communicable disease mortality reduction target: a modelling study

Cited by 370 publications

References 62 publications

Doenças Crônicas Não Transmissíveis: perfil da mortalidade no município de Natal/RN no período de 2000 a 2014

Doenças Crônicas Não Transmissíveis: perfil da mortalidade no município de Natal/RN no período de 2000 a 2014

Diez años del Convenio Marco de la OMS para el Control del Tabaco: avances en las Américas

Less is more: the dynamic epidemiology of cardiovascular diseases

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