Book of Proceedings of the Second All-Russian Scientific Conference With International Participation "Regulation Mechanisms of 2018
DOI: 10.31255/978-5-94797-318-1-136-138
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Abstract: Many lines of evidence suggest that decreased mitochondrialfunction is a hallmark of aging and that mitochondrialdysfunction has a central role in Alzheimer's disease (AD), the most common type of age-related dementia worldwide, which has no cure. The central role of mitochondria in aging was first proposed by Denham Harman, on the basis of his original theory that aging is caused by the accumulation of damage resulting from reactive oxygen species (ROS) (Harman, 2009). However, recent findings suggest that fo… Show more

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