Contribution of bacteriology and virology in sudden unexpected death in infancy

Prtak, Laura; Al-Adnani, Mudher; Fenton, Paul; Kudesia, Goura; Cohen, Marta C.

doi:10.1136/adc.2009.162792

Cited by 41 publications

(34 citation statements)

References 7 publications

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“…The causes of SUDID vary in the different published series. In accordance with previous reports, the main causes of SUDID in Biscay were myocarditis [5,7,9,10,14] and bronchopneumonia [4][5][6]12]. In our study, it is noteworthy that two-thirds of SUDIDs were due to these two diseases.…”

Section: Discussionsupporting

confidence: 93%

“…As reported in other studies, SUDID is mainly due to respiratory diseases and, to a lesser extent, to cardiac diseases [4][5][6][7][8][9][10][11][12][13][14]. By contrast, neurological SDs are rarely infectious.…”

Section: Discussionmentioning

confidence: 73%

“…SD was defined as that which occurs naturally (non-violent), unexpectedly and within a period of few hours from the beginning of the warning symptoms in a person in an apparently good state of health who has not been admitted to hospital and who is performing everyday activities at the time of the beginning of the symptoms [4,13,16]. In the unwitnessed deaths or those occurring during sleep, data were included when these people had been seen in a good state of health in the 24 h before their death.…”

Section: Data From the Forensic Pathology Servicementioning

confidence: 99%

“…In these sudden deaths (SDs), a forensic autopsy is required and microbiological analyses are needed to identify the aetiology of the infection [2]. The relevance of performing microbiological investigations in sudden unexpected deaths in infancy has been pointed out in recent articles [3,4].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Clinicopathological features of sudden unexpected infectious death: Population-based study in children and young adults

Morentín¹,

Suárez-Mier

Aguilera

et al. 2012

Forensic Science International

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 73%

Section: Data From the Forensic Pathology Servicementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinicopathological features of sudden unexpected infectious death: Population-based study in children and young adults

Morentín¹,

Suárez-Mier

Aguilera

et al. 2012

Forensic Science International

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“…An opinion should be expressed on the relevance of positive and negative bacteriology and virology culture findings in the light of the particular postmortem interval. 22 The final diagnosis should list all the anatomic and ancillary abnormalities that contributed to the death of the patient in order of their importance. In addition, the pathologist should provide an interpretation of the sequence of events leading to death.…”

Section: Resultsmentioning

confidence: 99%

The Pediatric Autopsy in Africa

Kaschula

2013

Archives of Pathology &Amp; Laboratory Medicine

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Context.-Within the continent of Africa few countries have been able to practice pathology at the levels present in Europe and the Americas, and pediatric pathology does not exist as a stand-alone specialty. The author was invited by a colleague from Harvard Medical School, Boston, Massachusetts, to join a group of North American pathologists in presenting a course on the Contribution of Anatomic Pathology for advancing the health of women and children in Africa. The course was held in Ethiopia in June 2011, to review the current state of pediatric pathology in Africa and to provide resources/teaching for improving pediatric pathology services in low-resource settings.Objective.-To provide a succinct description of applicable autopsy techniques and the interpretation of gross, microscopic, and ancillary findings with respect to Africa's need to enhance the health of women and children. The author makes suggestions for obviating possible problems in anticipation of increased demands by national authorities and of public expectations of pathologists who usually have had only general training.Data Sources.-This article is based upon the author's personal experience of practicing pathology in Africa for the past 51 years, which has included visiting pathology laboratories in 9 African countries and interacting with colleagues in 18 additional African countries. The contents of this article are derived from personal observations, recent publications, and information gleaned from Internet sources.Conclusions.-Even without specific training in pediatric pathology, it is possible for pediatric autopsies to be undertaken in Africa and other resource-poor settings, in a manner that facilitates sound decision making for improving the health of women and children.(Arch Pathol Lab Med. 2013;137:756-766; doi: 10.5858/ arpa.2011-0589-RA) T here are several published textbooks [1][2][3][4][5][6] that describe how pediatric autopsies should be undertaken and adapted for particular circumstances. This article attempts to describe methods that are appropriate for general pathologists who practice in Africa and have not received specific training in pediatric autopsy techniques. These suggestions are adaptable to any resource-poor setting and are useful for application by any pathologist with any level of training. Africa has the highest maternal, perinatal, and infant mortality rates in the world, and unfortunately, these have not changed significantly in the past 2 decades. Much effort and resource expenditures have gone into addressing underlying socioeconomic, educational, cultural, and environmental factors without having given adequate attention to the skills and facilities needed to make accurate diagnoses upon which appropriate interventions should be made. It therefore is essential that pediatric autopsies be undertaken by appropriately skilled pathologists having access to affordable resources and who can be confident that health care decision makers will use their diagnoses. In Africa the role of pathologists in the over...

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Sudden Infant Death Syndrome: Postmortem Investigation and Risk Factors

Cohen

2011

Wiley Encyclopedia of Forensic Science

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Sudden infant death syndrome (SIDS) is the largest single “category” of sudden unexpected death in infancy (SUDI) in babies over 1 month old in developed countries. SIDS is defined as the sudden death of an infant under 1 year of age, which remains unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. SIDS is, consequently, a diagnosis by exclusion and the result of a “negative” postmortem. The investigation of any case of SUDI is best conducted using a multidisciplinary approach. Only when the recognized causes of death are excluded is it appropriate to label the death as due to SIDS. In addition, it is best to arrive at this conclusion after a multidisciplinary inquiry. As data accumulates, the percentage of cases ascribed to SIDS diminishes.

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Contribution of bacteriology and virology in sudden unexpected death in infancy

Cited by 41 publications

References 7 publications

Clinicopathological features of sudden unexpected infectious death: Population-based study in children and young adults

Clinicopathological features of sudden unexpected infectious death: Population-based study in children and young adults

The Pediatric Autopsy in Africa

Sudden Infant Death Syndrome: Postmortem Investigation and Risk Factors

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