Contribution of antibiotics to the fate of antibiotic resistance genes in anaerobic treatment processes of swine wastewater: A review

Abstract

Antibiotic resistance genes (ARGs) in water environment have become a global health concern. Swine wastewater is widely considered to be one of the major contributors for promoting the proliferation of ARGs in water environments. This paper comprehensively reviews and discusses the occurrence and removal of ARGs in anaerobic treatment of swine wastewater, and contributions of antibiotics to the fate of ARGs. The results reveal that ARGs' removal is unstable during anaerobic processes, which negatively associated with the presence of antibiotics. The abundance of bacteria carrying ARGs increases with the addition of antibiotics and results in the spread of ARGs. The positive relationship was found between antibiotics and the abundance and transfer of ARGs in this review. However, it is necessary to understand the correlation among antibiotics, ARGs and microbial communities, and obtain more knowledge about controlling the dissemination of ARGs in the environment.

How synthetic biology can help bioremediation

“…PPCPs enter urban wastewater streams but are not removed by conventional treatment technologies and can recycle back into the food chain via their land application as fertilizers [14]. Furthermore, antimicrobial agents in PPCP waste have the potential to promote bacterial resistance in the environment [15].…”

Removal of antibiotic resistance genes during livestock wastewater treatment processes: Review and prospects

“…Livestock wastewater is an important repository for ARGs. Tetracyclines, aminoglycoside, sulfonamide, macrolide, streptomycin, bacitracin, β-lactam, chloramphenicol, quinolone, trimethoprim, fosmidomycin, polymyxin, and vancomycin resistance genes are frequently detected in wastewater, and the absolute abundance of ARGs is between 10 8 and 10 10 copies/mL, with a relative abundance between 10 −3 and 10 −1 copies/16S rRNA genes (10,(17)(18)(19). Among them, the abundance of tetracycline, aminoglycoside, macrolide-lincosamide-streptogramin (MLS), sulfonamide and chloramphenicol resistance genes were the highest, and they account for 28.13, 23.64, 12.17, 11.53, 8.74 and 6.18% of total ARGs respectively, and their abundances can be up to 2.41 × 10 −1 , 2.03 × 10 −1 , 1.04 × 10 −1 , 9.90 × 10 −2 , 7.49 × 10 −2 and 5.31 × 10 −2 copies/16S rRNA genes, respectively (19).…”

Biotransformación de antibióticos en humedales artificiales: Rol de la interacción entre microorganismos y macrófitas

“…Por ejemplo, en el caso de la oxitetraciclina y tetraciclina, las enzimas encargadas de su biodegradación son la lacasa, la manganeso peroxidasa, las glutatión S-transferasas y la monooxigenasa inactivadora (Shi et al 2021). También son capaces de generar genes resistentes a los antibióticos, los cuales se desarrollan en función del incremento de antibióticos en el ambiente (Cheng et al 2020). Knöppel et al (2017) indican que esta resistencia puede darse, incluso, en ausencia del antibiótico, ya que las bacterias son capaces de trasferir esa capacidad a otras bacterias a través de plásmidos e integrones (Wright 2010;Huang et al 2017) mediante la transformación, la transducción y la conjugación bacteriana (Furuya and Lowy 2006), incrementándose la cantidad de bacterias resistentes.…”