Contribution of anosmia and dysgeusia for diagnostic of COVID-19 in outpatients

Zayet, Souheil; Klopfenstein, Timothée; Mercier, Jean; Kadiane-Oussou, N’dri Juliette; Wah, Ludovic Lan Cheong; Royer, P; Toko, Lynda; Gendrin, Vincent

doi:10.1007/s15010-020-01442-3

Cited by 66 publications

(84 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…18,20,[24][25][26]29,32,34,37,[40][41][42][43][47][48][49][50][51][52][53][54][55][56][57][58][59] The remaining studies assessed olfactory ability through anamnestic data collection, simple surveys and/or structured, non-validated questionnaires (Table 4). 2,16,17,19,[21][22][23]27,28,30,31,33,35,36,38,39,[44][45][46]…”

Section: Resultsmentioning

confidence: 99%

Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review

et al. 2020

View full text Add to dashboard Cite

Objective Recent scientific literature has widely described a possible major role of smell dysfunction as a specific symptom of coronavirus disease 2019. This systematic review may provide a more holistic approach to current knowledge of the disease. Methods A systematic review was completed using Embase, PubMed and Web of Science databases that considered original articles focused on olfactory evaluation in coronavirus disease 2019 patients, published between March and May 2020, in English language. Results From the 483 research papers initially identified, 32 original studies were selected, comprising a total of 17 306 subjects with a laboratory confirmed diagnosis of coronavirus disease 2019. Individual study sample sizes ranged from 6 to 6452 patients. This comprehensive analysis confirmed that olfactory disorders represent an important clinical feature in coronavirus disease 2019, with a prevalence of 11–100 per cent in included patients, although there was heterogeneity in terms of assessment tools and population selection criteria. Conclusion The results indicate that an accurate clinical evaluation should be carried out using structured questionnaires and tests with olfactory substances.

show abstract

Section: Resultsmentioning

confidence: 99%

Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…On the one hand, in our setting the percentage of females amongst healthcare professionals is high. On the other hand, sex matters in COVID‐19, in which males are more prone to present severe pulmonary disorders, while headache or anosmia may be more frequent in females 38 …”

Section: Discussionmentioning

confidence: 99%

Spectrum of Headaches Associated With SARS‐CoV‐2 Infection: Study of Healthcare Professionals

et al. 2020

View full text Add to dashboard Cite

Background Series of patients with SARS‐CoV‐2 infection report headache in 6%‐15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients. Objective To analyze the characteristics of COVID‐19 related headaches. Methods We conducted a survey of Spaniard healthcare professionals who have been infected by SARS‐CoV‐2 and presented headache during the course of the disease. The survey addressed respondents’ medical history and headache characteristics, and we analyzed the association between both. Results We analyzed the responses of a sample of 112 healthcare professionals. History of migraine was reported by 20/112 (17.9%) of respondents, history of tension‐type headache by 8/112 (7.1%), and history of cluster headache was reported by a single respondent; 82/112(73.2%) of respondents had no history of headache. Headache presented independently of fever, around the third day after symptom onset. The previous history of migraine was associated with a higher frequency of pulsating headache (20% in patients with previous migraine vs 4.3% in those with no history of migraine, P = .013). Conclusion Headache is often holocranial, hemicranial, or occipital, pressing, and worsens with physical activity or head movements. Because the characteristics of the headache and the associated symptoms are heterogeneous in our survey, we suggest that several patterns with specific pathophysiological mechanisms may underlie the headache associated with COVID‐19.

show abstract

“…Among patients with flulike symptoms, the prevalence of SARS‐CoV‐2 infection may vary substantially according to geographic context and disease phase. For example, the study by Tostmann et al, conducted in The Netherlands during the early phase of the COVID‐19 pandemic, demonstrated a prevalence of 11% in SARS‐CoV‐2‒positive subjects among patients with a flulike illness, 7 whereas Zayet et al reported a prevalence of 44% in their cohort of patients evaluated in a French hospital 4 …”

Section: Figurementioning

confidence: 99%

“…Although its specificity is excellent, nasopharyngeal swab shows suboptimal sensitivity for SARS‐CoV‐2 detection in the early phase of infection being inconsistent during serial testing 3 . Moreover, patients developing COVID‐19‒related symptoms may be referred to nasopharyngeal swab later during the course of the disease when viral load is no longer detectable 4,5 . Thus, the diagnostic performance of new onset of smell and/or taste impairment for COVID‐19 may be even higher than estimated.…”

Section: Figurementioning

confidence: 99%

See 1 more Smart Citation

Challenges in interpreting the diagnostic performance of symptoms to predict COVID‐19 status: The case of anosmia

Boscolo‐Rizzo

Borsetto

Hopkins

et al. 2020

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Contribution of anosmia and dysgeusia for diagnostic of COVID-19 in outpatients

Cited by 66 publications

References 14 publications

Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review

Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review

Spectrum of Headaches Associated With SARS‐CoV‐2 Infection: Study of Healthcare Professionals

Challenges in interpreting the diagnostic performance of symptoms to predict COVID‐19 status: The case of anosmia

Contact Info

Product

Resources

About