Contributing Factors to the Quality of Life in Multiple Sclerosis

Šehanović, Aida; Kunić, Suljo; Ibrahimagić, Omer Ć.; Smajlović, Dževdet; Tupković, Emir; Mehičević, Admir; Zoletic, Emina

doi:10.5455/medarh.2020.74.368-373

Cited by 7 publications

(4 citation statements)

References 38 publications

(13 reference statements)

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“…Contudo, numa primeira análise, é de suma importância ressaltar que a QV está intimamente associada ao número e à gravidade dos sintomas, além do comprometimento causado pela EM na vida do paciente (GIL-GONZÁLEZ et al, 2020). Ou seja, assim que o estado de incapacidade trazido pela doença aumenta, piores são as condições de saúde física e mental e, consequentemente, pior é o bem-estar (SEHANOVIC et al, 2020).…”

Section: Discussionunclassified

Esclerose múltipla e qualidade de vida: abordagens para a inclusão do bem-estar

Melo,

Almeida,

Silva

et al. 2024

PRW

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A Esclerose Múltipla (EM) é a doença considerada o distúrbio desmielinizante mais frequente do Sistema Nervoso Central. A EM é caracterizada por apresentar um polimorfismo de sintomas e por possuir causa e etiologia desconhecidas, o que torna a escolha de tratamentos de melhor prognóstico um desafio. Logo, este trabalho possui como objetivo identificar os fatores que comprometem o bem-estar dos portadores da doença e apresentar terapias alternativas que ajudem na melhora da qualidade de vida (QV) dos pacientes. Trata-se uma revisão integrativa de literatura, a qual utilizou como critério artigos publicados entre 2019 e 2023, que abordassem o tema pesquisado e que estivessem disponíveis eletronicamente em seu formato integral, encontrados nas bases de dados Google Scholar, Biblioteca Virtual de Saúde, EBSCO, PubMed e SciELO. Os resultados avaliados mostraram que os diferentes sintomas relacionados com EM e sua progressão, como a dificuldade de locomoção, fadiga e depressão, são a causa de uma notável diminuição da QV nos portadores da doença. Já a utilização de terapias alternativas e complementares, é de extrema importância clínica. Contudo, ressalta-se a importância de novos estudos acerca do assunto.

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Section: Discussionunclassified

Esclerose múltipla e qualidade de vida: abordagens para a inclusão do bem-estar

Melo,

Almeida,

Silva

et al. 2024

PRW

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“…Cerezo Garcia et al (25) reported impairment in executive functions, while Hoffman et al (31) found impairment in working memory in most participants. Sehanovic et al (32) showed that 40-60% of patients with MS had impaired cognitive functions and that this effect became more manifest with an increase in disease duration. Consistent with the above studies, the results of the present study indicated that memory impairment in patients with MS was positively associated with disease duration, and also with disease severity.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Patients with Multiple Sclerosis in Terms of Memory, Attention, Executive Functions, Fine Motor Movement and the Association thereof with Magnetic Resonance Imaging Results

Sahin,

Kılıçaslan Şahin,

Dağ

2024

Düzce Tıp Fakültesi Dergisi

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Aim: This study aimed to review cognitive function and fine motor skills in patients with multiple sclerosis (MS) and investigate the association with magnetic resonance imaging (MRI) results. Material and Methods: The study included 22 patients diagnosed with relapsing-remitting MS and 22 controls. Participants underwent neuropsychological tests, including the Stroop test, Rey auditory verbal learning test (RAVLT), line bisection test (LBT), serial reaction time test (SRTT), and finger tapping test (FTT). The relationship between severity of disease, MRI, and test performance was investigated. Results: It was determined that the patients were lateralized to the right in the LBT data, while the control group was lateralized to the left (p=0.024). On cognitive tests, there was no significant difference in Stroop test results (p=0.134), but the mean overall RAVLT of the patient group was significantly lower than that of the control group (p

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“…Gait, balance, and fall risk were evaluated using the Dynamic Gait Index (DGI) (Forsberg et al, 2013). Impact of MS on walking ability and health-rated quality of life was assessed using the Multiple Sclerosis Walking Scale -12 (MSWS-12) and the 36-Item Short-Form Health Survey questionnaire (SF-36) respectively (Hobart et al, 2003;Sehanovic et al, 2020).The severity and behavioral characteristics of depression and anxiety were evaluated using the self-report questionnaires Beck Depression Inventory -Second Edition (BDI-II) and State-Trait Anxiety Inventory (STAI-Y), respectively (Santangelo et al, 2016;Sica & Ghisi, 2007). Effects of ctDCS on executive functions were evaluated using the subtest "Go/Nogo" of the Test Battery for Attention (TAP), a response inhibition task (Zimmermann & Fimm, 2002).…”

Section: Methodsmentioning

confidence: 99%

Combined effects of cerebellar tDCS and task-oriented circuit training in people with multiple sclerosis: A pilot randomized control trial

Baroni

Magro

Martinuzzi

et al. 2022

RNN

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Background: Balance and mobility impairments are frequent in people with multiple sclerosis, partly due to cerebellar dysfunctions. Task-oriented behavioural approaches were previously shown to promote physical function. The possibility exists that cerebellar transcranial direct current stimulation (ctDCS) applied during training, known to increase the excitability of the brain, can boost rehabilitation effects through modulation of cerebellum-brain inhibition. Objective: To test the efficacy of cerebellar ctDCS stimulation combined with motor training on mobility and balance in people with multiple sclerosis. Methods: 16 subjects were randomly assigned to receive real- or sham-ctDCS and task-oriented training daily over two weeks in a double-blind, randomised clinical pilot trial. Functional mobility, balance, walking performance and quality of life were tested before and after treatment and at two-week follow-up. Effects of cerebellar stimulation on psychological and executive functions were also recorded. Results: Walking performance, balance and quality of life improved for both groups at post-treatment assessment which was maintained at 2-weeks follow up. A two-way ANOVA revealed a significant time effect for balance and walking performance. A significant interaction effect of time–treatment (F = 3.12, df = 2,26; p = 0.03) was found for motor aspects of quality of life assessment in patients who received real-ctDCS. Conclusions: Task-oriented training improves balance and mobility in people with multiple sclerosis, but ctDCS does not boost motor training effects.

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Contributing Factors to the Quality of Life in Multiple Sclerosis

Cited by 7 publications

References 38 publications

Esclerose múltipla e qualidade de vida: abordagens para a inclusão do bem-estar

Esclerose múltipla e qualidade de vida: abordagens para a inclusão do bem-estar

Evaluation of Patients with Multiple Sclerosis in Terms of Memory, Attention, Executive Functions, Fine Motor Movement and the Association thereof with Magnetic Resonance Imaging Results

Combined effects of cerebellar tDCS and task-oriented circuit training in people with multiple sclerosis: A pilot randomized control trial

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