Contributing Factors to Colorectal Cancer Screening among Chinese People: A Review of Quantitative Studies

Leung, Doris Y. P.; Chow, Ka Ming; Lo, Sally Wai Sze; So, Winnie K.W.; Chan, Carmen W.H.

doi:10.3390/ijerph13050506

Cited by 29 publications

(31 citation statements)

References 45 publications

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“…Patient at earlier stages had a significant improvement in survival. This finding underlines the importance of early diagnosis and increased awareness of CRC in China [34,35].…”

Section: Discussionmentioning

confidence: 53%

Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China

Wang

Zhu

et al. 2020

BMC Cancer

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Background: Colorectal cancer (CRC) is the third most prevalent cancer in China but few large-scale studies were conducted to understand CRC patients. The current study is aimed to gain a real-world perspectives of CRC patients in China.Methods: Using electronic medical records of sampled patients between 2011 and 2016 from 12 hospitals in China, a retrospective cohort study was conducted to describe demographics and disease prognosis of CRC patients, and examine treatment sequences among metastatic CRC (mCRC) patients. Descriptive, comparative and survival analyses were conducted. Results: Among mCRC patients (3878/8136, 48%), the fluorouracil, leucovorin, and oxaliplatin (FOLFOX) and other oxaliplatin-based regimens were the most widely-used first-line treatment (42%). Fluorouracil, leucovorin, irinotecan (FOLFIRI) and other irinotecan-based regimens dominated the second-line (40%). There was no a dominated regimen for the third-line. The proportion of patients receiving chemotherapy with targeted biologics increased from less than 20% for the first-and second-lines to 34% for the third-line (p < 0.001). The most common sequence from first-to second-line was from FOLFOX and other oxaliplatin-based regimens to FOLFIRI and other irinotecan-based regimens (286/1200, 24%). Conclusions:Our findings reflected a lack of consensus on the choice of third-line therapy and limited available options in China. It is evident o continue promoting early CRC diagnosis and to increase the accessibility of treatment options for mCRC patients. As the only nationwide large-scale study among CRC and mCRC patients before more biologics became available in China, our results can also be used as the baseline to assess treatment pattern changes before and after more third-line treatment were approved and covered into the National Health Insurance Plan in China between 2017 and 2018.

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“…Patient at earlier stages had a significant improvement in survival. This finding underlines the importance of early diagnosis and increased awareness of CRC in China [34,35].…”

Section: Discussionmentioning

confidence: 53%

Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China

Wang

Zhu

et al. 2020

BMC Cancer

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“…Regarding the low rates of CRC screening, some factors affecting participation like socio-demographic characteristics (educational level, health insurance, and knowledge of CRC and CRC screening), psychological factors (perceived severity of CRC, susceptibility to CRC, and barriers to screening), and contact with medical provider (physician recommendation) could be considered. [44] To improve participation in CRC screening in China, more studies are clearly needed to address these points including a longer follow-up of the present study, to better inform the citizens regarding the benefits of CRC screening.…”

Section: Discussionmentioning

confidence: 99%

Low rate of follow-up colonoscopy after positive results of colorectal cancer screening in a Chinese urban core district

Guo

Jiang

Tanimoto

et al. 2019

Preprint

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52Colorectal cancer (CRC) is one of the most common cancers in China. In 2003, a systematic CRC 53 registry that enables the determination of CRC incidence and mortality and a CRC screening project 54 were introduced in the Jing'an district of Shanghai by the municipal government. This study assessed 55 the registry data to determine the status of CRC and CRC screening rates in the core district of an 56 urban area of China. Data were retrieved from the Official registry information systems of Jing'an 57 district Shanghai Cance. The incidence and mortality of CRC, as well as population-based CRC 58 screening rates, were analysed. Individuals who screened positive for CRC based upon results of a 59 high-risk factor questionnaire (HRFQ) and a faecal immunochemical test (FIT) were selected for 60 follow-up colonoscopy (CSPY). From the registry data collected between 2003 and 2013, the 61 standardized incidence rate was 26.44/10 5 , with a significant gender difference. The CRC 62 standardized mortality rate was 10.08/10 5 . In 2013, 17,866 individuals (21.6%) enrolled for CRC 63 screening among the 82,602 candidate residents. The positive screening rate was 16.28% 64(2909/17866). Among the 2909 positives, 508 (17.5%) underwent follow-up CSPY. In 41.3% of 65 these individuals (210/508), abnormal lesions were detected. Of these, 8 (1.57%) lesions were 66 diagnosed as CRC, and 142 (28.0%) were identified as precancerous lesions. During the assessment 67 period, both the incidence and mortality of CRC in the Jing'an district were determined in the area of 68 high CRC prevalence in Chin. Nevertheless, the rate of participation in CRC screening was low 69 (21.6%), and the rate of participation in follow-up CSPY for individuals who screened positive was 70 only 17.5%. Improved participation in CRC screening and follow-up CSPY is expected to lower the 71 incidence and mortality of CRC significantly in the rural areas of China. (288) 72 73 74 75 76 77 78 79 80 4 81 82 131 CDC (Shanghai Jingan Center for Disease Control and Prevention), through the Shanghai Cancer 132 Registry Information System and the Shanghai All Causes of Death Registration Reporting System 133 organized by the Shanghai Government and Jingan municipal office. 134 135 The CRC screening was conducted by six sites of the community health service center in this district 136 under supervise by the health bureau of the Shanghai Government and Jingan municipal office. 137 Colonoscopy and the follow-up diagnosis for further treatment under supervise by the health bureau 138 were performed in the four designated hospitals (Jing'an District Central hospital, Huashan hospital, 139 Huadong hospital and Post & Telecommunications Hospital of Shanghai.).140 307 assessment and development of other assessments are in progress[24-29], the FIT used in this study 308 appears reliable and appropriate for CRC screening at this stage.309 310 Follow-up colonoscopy (CSPY) is indispensable for reducing CRC mortality in individuals who 311 screen positive for CRC 312 CSPY is c...

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“…However, only a few of the studies in this review examined screening test related factors, such as perceived screening effectiveness. Another recent review on Chinese adults also reported similar factors that influence CRC screening behavior [ 15 ]. As noted in this recent review, only a few of the reviewed studies utilizing current health theories to guide the inquiry.…”

Section: Introductionmentioning

confidence: 95%

“…Numerous systematic reviews of demographic, social, and environmental determinants of CRC screening have been produced in the last few decades [ 10 , 11 , 12 , 13 , 14 , 15 ]. The single systematic review of 83 studies focusing on people aged ≥65 revealed a number of demographic variables (educational level, race, ethnicity, gender, marital status, and living status) and health-care systems related variables (recommendation by physicians, having a usual source of care, and lack of health insurance) were important factors to the uptake of CRC screening tests [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Promotional Materials on Attitudes and Fear towards Colorectal Cancer Screening among Chinese Older Adults: An Experimental Study

Leung

Chen

Lou

et al. 2017

IJERPH

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Colorectal cancer (CRC) screening is a cost-effective prevention and control strategy. However, the promotion of CRC screening for older adults may be difficult because reading CRC prevention information may evoke embarrassment, fear, and anxiety towards the screening procedure and cancer diagnosis. This study aims to (1) examine the effects of three promotional materials for CRC screening on the attitudes toward CRC screening tests (screening interest, screening effectiveness, and trust in the screening results) and cancer fear, and (2) to explore the interaction effect of cancer fear with screening effectiveness and trust in the screening results on screening interest of the three screening tests (fecal occult blood test (FOBT), flexible sigmoidoscopy, and colonoscopy) among Chinese older adults. A total of 114 community-dwelling older adults were asked to look at the corresponding promotional materials (pamphlet, cartoon, and video) of one of the three study groups. The pamphlet and video represent convention strategies and the cartoon represents an innovative strategy. No significant difference was observed in the screening interest and cancer fear across groups. FOBT was the most preferred screening modality. The video group has a large proportion agreed screening effectiveness of flexible sigmoidoscopy than pamphlet and cartoon groups and trusted in the screening results for FOBT and flexible sigmoidoscopy than the pamphlet group. Logistic regression results showed that the effect of trust in the screening results on screening interest for colonoscopy was greater among participants with higher cancer fear than those with lower cancer fear level. In conclusion, the three promotional groups had produced similar results in their attitudes toward CRC screening and cancer fear. The use of cartoons may be a comparable approach with conventional methods in the promotion of CRC screening. Additional components that can arouse fear and boost response efficacy simultaneously might also be useful for the effective promotion of colonoscopy among Chinese older adults.

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Contributing Factors to Colorectal Cancer Screening among Chinese People: A Review of Quantitative Studies

Cited by 29 publications

References 45 publications

Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China

Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China

Low rate of follow-up colonoscopy after positive results of colorectal cancer screening in a Chinese urban core district

Effects of Promotional Materials on Attitudes and Fear towards Colorectal Cancer Screening among Chinese Older Adults: An Experimental Study

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