1993
DOI: 10.1007/978-3-642-77369-3_5
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Contrast Medium Induced Nephropathy: Animal Experiments

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Cited by 22 publications
(7 citation statements)
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“…Reverse movement from the extracellular space into the intravascular compartment occurs, and a state of equilibrium is generally reached within 2 h. Continuous elimination through the glomeruli also occurs. Less than 1 % is excreted extrarenally in patients with normal renal function (Thomsen et al 1993). Following intravascular administration in patients with normal renal function, the elimination half-life of contrast media is about 2 h, and 75 % of the administered dose is excreted in the urine within 4 h (Katzberg 1997).…”
Section: Renal Handling Of Contrast Mediamentioning
confidence: 99%
“…Reverse movement from the extracellular space into the intravascular compartment occurs, and a state of equilibrium is generally reached within 2 h. Continuous elimination through the glomeruli also occurs. Less than 1 % is excreted extrarenally in patients with normal renal function (Thomsen et al 1993). Following intravascular administration in patients with normal renal function, the elimination half-life of contrast media is about 2 h, and 75 % of the administered dose is excreted in the urine within 4 h (Katzberg 1997).…”
Section: Renal Handling Of Contrast Mediamentioning
confidence: 99%
“…It is mainly excreted through the kidneys with less than 1% eliminated via extrarenal routes in patients with normal kidney function. [ 48 ] The half-life of CM is about 2 h with 75% excreted within 4 h and 98% within 24 h.[ 49 50 ]…”
Section: Nonpharmacological Approachmentioning
confidence: 99%
“…This is not surprising since CM administration does not normally induce CIN and morbidity justifying renal biopsy. Thus, most of the morphological description of these changes is based on experimental in vitro and in vivo animal studies (6,7,9,12,30,34,35,37,50,51,(53)(54)(55). Furthermore, there is only scant literature describing histomorphological renal changes after administration of Gd-CM (2,22,50,53).…”
mentioning
confidence: 99%