Contrast-enhanced ultrasound of the pancreas

D’Onofrio, Mirko; Gallotti, Anna; Principe, Francesco; Mucelli, Roberto Pozzi

doi:10.4329/wjr.v2.i3.97

Cited by 41 publications

(28 citation statements)

References 54 publications

(84 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, its quantitative diagnostic ability is limited [2]. Major limitations are the occasionally restricted image resolution due to the lesions' location (especially in the pancreatic tail) and to the poor sonographic visualization of the gland, due to overlying abdominal gas or to large amounts of abdominal fat [5].…”

Section: Discussionmentioning

confidence: 99%

“…Thus, CEUS can aid in the differential diagnosis of pancreatic tumors [4] and can provide dynamic information, with a high temporal and spatial resolution, concerning macro and micro-circulation of focal lesions and normal parenchyma [3,6]. Its high capability in showing tumoral microcirculation also makes CEUS accurate in the study of neoangiogenesis [5,7]. But CEUS has the disadvantage of being an operator-dependent method, and also its accuracy is influenced by the patients' acoustic window, an important aspect to be taken into consideration when evaluating a pancreatic lesion.…”

Section: Introductionmentioning

confidence: 99%

“…The introduction of contrast-enhanced ultrasound (CEUS) has improved the diagnostic accuracy of US and extended its value [3,4]. The innovative use of CEUS for the study of the pancreas created the need for a precise definition of the most dynamic features of pancreatic masses (solid and cystic) [5]. Thus, CEUS can aid in the differential diagnosis of pancreatic tumors [4] and can provide dynamic information, with a high temporal and spatial resolution, concerning macro and micro-circulation of focal lesions and normal parenchyma [3,6].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The value of Contrast-Enhanced Ultrasound in the characterization of vascular pattern of solid pancreatic lesions

et al. 2015

View full text Add to dashboard Cite

The aim of our study was to evaluate the accuracy of CEUS in the characterization of pancreatic solid lesions, considering cross sectional imaging techniques (CE-CT/MRI) as the "gold standard" methods. Material and methods: We performed a retrospective, monocentric study that included 91 solid pancreatic lesions which were evaluated by CEUS and by a secondline contrast imaging technique (CT or MRI), considered as the reference method. Results: The rate of a conclusive diagnosis based on a typical enhancement pattern was 94% (78/83 cases). In 72 cases out of 83 (86.7%) there was a perfect concordance between CEUS and the "gold-standard" imaging method (CE-CT/MRI). In our study, 88% (73/83) of the pancreatic lesions were categorized as malignant due to their typical wash-out aspect in the late phase. The overall accuracy of CEUS for the differential diagnosis of solid pancreatic tumors was approximately 81%. The accuracy of CEUS for the diagnosis of hypoenhancing pancreatic tumors was approximately 89.1%; while for the diagnosis of hyperenhancing pancreatic tumors it was approximately 72.8%. Conclusion: CEUS allows the differentiation between hypo-vs. hyperenhancing pancreatic solid lesions, with a considerable diagnostic accuracy, a fundamental step in the precise diagnosis of pancreatic tumors.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The value of Contrast-Enhanced Ultrasound in the characterization of vascular pattern of solid pancreatic lesions

et al. 2015

View full text Add to dashboard Cite

show abstract

“…It has led to major improvements in the diagnostic capabilities of conventional US (D′Onofrio et al, 2010). For PCNs, CEUS gives a good view of the septa and mural nodules.…”

Section: Contrast Enhanced Ultrasound (Ceus)mentioning

confidence: 99%

Pancreatic cystic neoplasms: a review of preoperative diagnosis and management

Bai

Zhang

Masood

et al. 2013

J. Zhejiang Univ. Sci. B

View full text Add to dashboard Cite

Pancreatic cystic neoplasms (PCNs) are a diverse group of neoplasms in the pancreas, and are more increasingly encountered with widespread abdominal screening and improved imaging techniques. The most common types of PCNs are serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), and intraductal papillary mucinous neoplasms (IPMNs). Clinicians frequently feel bewildered in the differential diagnosis and subsequent management among the various types of lesions in the pancreas, which may lead to overtreatment or delayed treatment. The current review provides recent developments in the understanding of the three most common types of PCNs, the latest modalities used in preoperative diagnosis and differential diagnosis, as well as the most up to date management. Suggestions for diagnosis and differential diagnosis of SCNs, MCNs, and IPMNs are also provided for young surgeons. Better understanding of these neoplasms is essential for clinicians to make accurate diagnosis and to provide the best management for patients.

show abstract

“…The criteria used for the differential diagnosis of pancreatic masses (standard US, Doppler US and CEUS) are presented in Several studies proved the utility of CEUS for the characterization of pancreatic tumors [2,9,17,[47][48][49]. The accuracy for the diagnosis of solid pancreatic lesions varies from 91.7% [2] to 92.9% [17] or 93.8% in other series [48].…”

Section: Serous Cystadenomasmentioning

confidence: 99%

Contrast‐Enhanced Ultrasound for the Assessment of Pancreatic Lesions

Şirli¹,

Popescu²

2017

Challenges in Pancreatic Pathology

View full text Add to dashboard Cite

Transabdominal ultrasound (US) is the first-line imaging method used to diagnose pancreatic lesions, but contrast techniques are needed to differentiate among inflammatory and malignant lesions, as well as between pseudocysts and cystic tumors. Contrast-enhanced (CE) ultrasonography has been proven to be a useful tool in this regard with performance similar to contrast-enhanced computer tomography/magnetic resonance imaging (CT/MRI), being also safer and nonirradiant. According to the EFSUMB guidelines on the nonhepatic use of contrast-enhanced ultrasound (CEUS), this method is useful to improve characterization of ductal adenocarcinoma; to differentiate between pseudocysts and cystic tumors; to differentiate vascular (solid) from avascular (liquid/necrotic) components of a lesion; to better define the dimensions and margins of a lesion, including its relationship with adjacent vessels; and to help the choice for a next imaging technique.

show abstract

Contrast-enhanced ultrasound of the pancreas

Cited by 41 publications

References 54 publications

The value of Contrast-Enhanced Ultrasound in the characterization of vascular pattern of solid pancreatic lesions

The value of Contrast-Enhanced Ultrasound in the characterization of vascular pattern of solid pancreatic lesions

Pancreatic cystic neoplasms: a review of preoperative diagnosis and management

Contrast‐Enhanced Ultrasound for the Assessment of Pancreatic Lesions

Contact Info

Product

Resources

About