Contrast enhanced ultrasound (CEUS) in Pregnancy: Is this the last frontier for microbubbles?

Sidhu, Paul S.; Huang, Dean Y.; Fang, Cheng

doi:10.1055/a-0964-9827

Cited by 10 publications

(7 citation statements)

References 19 publications

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“…The patient later underwent an ultrasound-guided biopsy, and definite verification by histopathology was done. As recently demonstrated, CEUS proved a safe and reliable imaging tool to make contrast-enhanced (maternal) investigations during pregnancy feasible [ 63 , 64 , 65 ]. It could be shown that SonoVue ® did not cross the placental barrier [ 66 ].…”

Section: Discussionmentioning

confidence: 99%

Advanced Fusion Imaging and Contrast-Enhanced Imaging (CT/MRI–CEUS) in Oncology

Schwarze

Rübenthaler

Marschner

et al. 2020

Cancers

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Fusion imaging depicts an innovative technique that facilitates combining assets and reducing restrictions of advanced ultrasound and cross-sectional imaging. The purpose of the present retrospective study was to evaluate the role of fusion imaging for assessing hepatic and renal lesions. Between 02/2011–08/2020, 92 patients in total were included in the study, of which 32 patients had hepatic lesions, 60 patients had renal lesions. Fusion imaging was technically successful in all patients. No adverse side effects upon intravenous (i.v.) application of SonoVue® (Bracco, Milan, Italy) were registered. Fusion imaging could clarify all 11 (100%) initially as indeterminate described hepatic lesions by computed tomography/magnetic resonance imaging (CT/MRI). Moreover, 5/14 (36%) initially suspicious hepatic lesions could be validated by fusion imaging, whereas in 8/14 (57%), malignant morphology was disproved. Moreover, fusion imaging allowed for the clarification of 29/30 (97%) renal lesions initially characterized as suspicious by CT/MRI, of which 19/30 (63%) underwent renal surgery, histopathology revealed malignancy in 16/19 (84%), and benignity in 3/19 (16%). Indeterminate findings could be elucidated by fusion imaging in 20/20 (100%) renal lesions. Its accessibility and repeatability, even during pregnancy and in childhood, its cost-effectiveness, and its excellent safety profile, make fusion imaging a promising instrument for the thorough evaluation of hepatic and renal lesions in the future.

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Section: Discussionmentioning

confidence: 99%

Advanced Fusion Imaging and Contrast-Enhanced Imaging (CT/MRI–CEUS) in Oncology

Schwarze

Rübenthaler

Marschner

et al. 2020

Cancers

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“…Subsequently, the mixture was boiled for 60 min and filtered. The dregs were then added to water, and the above steps were repeated [ 39 ].…”

Section: Methodsmentioning

confidence: 99%

Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism

Yan

Liu

Yuan

et al. 2021

Aging

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We investigated the mechanisms underlying the therapeutic effects of Yiqi Jiemin decoction (YJD), a traditional Chinese medicine (TCM), in the ovalbumin (OVA)-induced allergic rhinitis (AR) model in guinea pigs. YJD significantly decreased infiltration of mast cells and eosinophils into the nasal mucosa of AR model guinea pigs. YJD also increased expression of TGF-β in the nasal mucosa, restored the balance of Th1/Th2 immune cell responses, and decreased serum levels of various pro-inflammatory mediators, including histamine (HA), neuropeptide Y (NPY), acetylcholine (ACH), norepinephrine and immunoglobulin E (IgE). Metabolic analyses using liquid chromatography coupled with high-resolution mass spectrometry revealed that YJD improved cellular metabolism in AR model guinea pigs and increased serum levels of glycocholic acid while decreasing levels 1-palmitoyl lysophosphatidic acid. RNA-sequencing analysis identified BPIFB2 as a potential diagnostic biomarker and therapeutic target for AR. Functional enrichment analyses showed that YJD significantly inhibited cytokine secretion pathways in AR model guinea pigs. These findings demonstrate that YJD protects against OVA-induced AR in guinea pigs by suppressing inflammation in the nasal mucosa, restoring Th1/Th2 balance, and improving cellular metabolism.

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“…Es gibt jedoch aktuell keine ausreichenden Daten bezüglich der Sicherheit dieser Untersuchung in der Schwangerschaft. Die erste prospektive multizentrische Studie ist geplant [7].…”

Section: Generelle Grundlagen Der Ceusunclassified

Contrast-enhanced ultrasound of the liver: basics and interpretation of common focal lesions

Safai Zadeh,

Prosch,

Ba-Ssalamah

et al. 2024

Rofo

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Over the past 20 years, contrast-enhanced ultrasound (CEUS) has become established as a procedure that is complementary to B-mode ultrasound and color Doppler sonography.The aim of this review is to provide the fundamental knowledge required for examining the liver with CEUS. Additionally, the characteristic CEUS patterns of frequent focal liver lesions are described.Considering the limitations of ultrasound, CEUS offers an equivalent alternative to other imaging modalities, such as computed tomography and magnetic resonance imaging, for evaluating focal liver lesions. It should be utilized as a primary modality due to its lack of radiation exposure and rapid availability. Key Points: Citation Format

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Contrast enhanced ultrasound (CEUS) in Pregnancy: Is this the last frontier for microbubbles?

Cited by 10 publications

References 19 publications

Advanced Fusion Imaging and Contrast-Enhanced Imaging (CT/MRI–CEUS) in Oncology

Advanced Fusion Imaging and Contrast-Enhanced Imaging (CT/MRI–CEUS) in Oncology

Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism

Contrast-enhanced ultrasound of the liver: basics and interpretation of common focal lesions

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