Contrast-enhanced ultrasonography in chronic glomerulonephritides: correlation with histological parameters of disease activity

Nestola, Manuela; Matthaeis, Nicoletta De; Ferraro, Pietro Manuel; Fuso, Paola; Costanzi, Stefano; Zannoni, Gian Franco; Pizzolante, Fabrizio; Quadra, Sabina Vasquez; Gambaro, Giovanni; Rapaccini, Gian Ludovico

doi:10.1007/s40477-018-0298-1

Cited by 3 publications

(1 citation statement)

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“…The early finding of an area of enhancement in the operated kidney at CECT during follow-up represents a diagnostic challenge, considering the possible recurrence of the disease or a false positive (pseudoenhancement, granuloma, etc.) [25,[31][32][33][34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

Surgical margin follow-up after nephron-sparing surgery: the possible role of CEUS

et al. 2019

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Purpose To evaluate the possible role of CEUS in the management of patients who underwent nephron-sparing surgery (NSS) and presented questionable findings on the surgical margins at the CECT follow-up exam. Methods In our retro-prospective study, we included 952 patients with small renal masses (SRMs) treated with NSS between 2012 and 2015 and followed with CECT for at least 3 years at Careggi University Hospital. Twenty-two of them presented solid masses on the site of surgery with questionable enhancement at CECT and were further studied with CEUS. This examination was followed by a quantitative analysis of the enhancement pattern. Results Out of the 22 masses, 18 were considered possible granulomas, presenting slow wash-in and low enhancement peaks compared to the surrounding parenchyma and persistent delayed wash-out at CEUS. Four lesions presented a suspicious malignant enhancement pattern, with rapid wash-in, high peak and rapid wash-out. In accordance with instructions from the urologist, the first group of 18 patients was strictly monitored, revealing that the mass dimensions and enhancement pattern were stable for at least 3 years of follow-up, while the other 4 patients underwent a second intervention and their masses were confirmed as tumor recurrence at the histopathological evaluation. Conclusions CEUS can play a key role in the surgical margin follow-up after NSS when a suspicious enhancing mass is detected by CECT, giving an accurate depiction of the enhancement pattern and thus helping the clinician in the management of the patient.

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