“…Since the introduction to the market of more stable second generation ultrasound contrast agents, together with the introduction of harmonic ultrasound imaging, the technique of contrast enhanced voiding urosonography has proven to be valid and sensitive, in experienced hands, and is the procedure of choice in many central European countries to detect vesicoureteric reflux. The review papers in this issue give a detailed account of the technique, and discuss the safety issues together with the advantages of its use (4,5). While the relationship between urinary tract infection, vesicoureteric reflux and renal scarring remains controversial, and the indications for studies to detect reflux are decreasing, it is important where possible to use examinations which are not associated with radiation exposure.…”