Contrast‐enhanced timing robust acquisition order with a preparation of the longitudinal signal component (CENTRA plus) for 3D contrast‐enhanced abdominal imaging

Beck, G.; Becker, Jan De; Jones, Alun C.; Falkenhausen, M. von; Willinek, Winfried A.; Gieseke, Jürgen

doi:10.1002/jmri.21393

Cited by 26 publications

(18 citation statements)

References 23 publications

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“…We obtained four arterial-phase images at the same level using the "4D THRIVE CENTRA and keyhole" sequence [11][12][13]. In our study, the third-arterial phase was the most common phase (50%, 21/42), showing prominent peritumoral enhancement.…”

Section: Discussionmentioning

confidence: 93%

“…To the best of our knowledge, studies that have evaluated the histopathological vessel invasion status of HCC based on preoperative magnetic resonance imaging (MRI) findings are limited [9,10]. However, recent protocols such as the THRIVE-CENTRA-keyhole technique have potentially expanded the extent of clinical application of MRI by the acquisition of multiarterial phase dynamic studies, which might allow better evaluation of the dynamic properties of hepatic lesions with rapid perfusion characteristics [11,12].…”

Section: Introductionmentioning

confidence: 98%

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Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI?

et al. 2009

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Microvessel invasion is a major prognostic factor in hepatocellular carcinoma (HCC) that influences the suitability of surgery, but rarely can be evaluated preoperatively. This study was performed to identify preoperative MRI findings that reflect histopathological microvessel invasion in hepatocellular carcinoma. Gadobenate dimeglumine-enhanced four-arterial phase dynamic study and hepatobiliary phase images of preoperative MRI of 70 HCC lesions were retrospectively reviewed. Tumor size (cm), peritumoral enhancement, tumor margins, and radiological capsule were analyzed as radiological parameters reflecting microvessel invasion and were compared with histopathological references. The chi-square test and the independent t-test were used for univariate analysis, and a logistic regression analysis was performed for multivariate analysis. In univariate analysis, tumor size (p = 0.030), peritumoral enhancement (p < 0.001), and tumor margins (p = 0.007) were associated with microvessel tumor invasion. However, in multivariate analysis irregular circumferential peritumoral enhancement only showed statistical significance (odds ratio 13.0), suggesting a high probability of microvessel invasion of HCC. Irregular circumferential peritumoral enhancement on contrast-enhanced multi-arterial phase dynamic MRI could be a preoperative surrogate marker for microvessel tumor invasion.

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Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 98%

Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI?

et al. 2009

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“…The DCE MR imaging can be accelerated (time resolved) by dynamic profile sharing techniques such as dynamic elliptical centric keyhole, to obtain six dynamic scans with 75 slices, a spatial resolution of 2.0 9 2.5 9 2 mm and a temporal resolution of 1.9 s in a single 20 s breath-hold [51].…”

Section: Methodsmentioning

confidence: 99%

New acquisition techniques: fields of application

2011

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Conventional MR imaging of the liver has a central role in the assessment of liver diseases. Diffusion-weighted MR imaging, MR elastography, and time-resolved dynamic contrast-enhanced MR imaging improve the anatomical information provided by conventional MR imaging and add quantitative functional information in diffuse and focal liver diseases. Particularly, accurate detection and characterization of liver fibrosis are feasible with quantitative MR elastography, detection of liver tumors is increased with diffusion-weighted MR imaging and time-resolved dynamic contrast-enhanced MR imaging, characterization of tumors can be improved with quantitative diffusion-weighted MR imaging and MR elastography. These methods also have the potential to provide adequate biomarkers for assessing the response to treatment. Currently, the main limitations of quantitative MR imaging are related to reproducibility, standardization, and/or limited clinical data. It is important to improve and standardize the quantitative MR methods and validate their role in large multicenter trials.

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“…According to alternating view sharing scheme as described, central disc of three phases are acquired first, and finally peripheral k-space date is acquired. (14) 6 (43) 3 (21) 5 (36) Hemangioma (%) (9) 6 (67) 3 (33) DN/RN (%) (8) 3 (38) 5 (62) Abscess (%) (6) 4 ( (Fig. 6).…”

Section: Figmentioning

confidence: 99%

Triple Arterial Phase Hepatic MRI Using Four Dimensional T1-Weighted High Resolutions Imaging with Volume Excitation Keyhole Techniques: Feasibility and Initial Clinical Experience in Focal Liver Lesions

Kim

Park

et al. 2013

J Korean Soc Radiol

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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose:To investigate a new image acquisition method [four dimensional T1-weighted high resolution imaging with volume excitation (4D THRIVE)] which enables an accurate hepatic arterial phase definition. The feasibility and its potential for detection and characterizing focal liver lesions (FLLs) are being evaluated. Materials and Methods: 115 FLLs underwent liver MRI that included the 4D THRIVE-contrast enhanced timing robust acquisition order (CENTRA)-keyhole sequence. Triple arterial phase was obtained during a single breath-hold. Images were reviewed for image quality, lesion conspicuity, and lesion detection. Two radiologists independently assessed images from phase I, II, III and through the triple arterial phase, which were all reviewed separately and in random order. The image quality was scored by using the five-point scale, and then, one phase for lesion with greatest conspicuity was selected. The enhancement pattern for FLLs was analyzed. Results: The detection rate was the highest on phase III. The image quality was greater than grade 3 with fair inter-observer agreements. The phase III showed greater conspicuity than phase I and II. Hepatocellular carcinomas (n = 38) showed variable enhancement pattern. Metastasis (n = 14) showed rim enhancement (n = 6), homogenous (n = 3) and no enhancement (n = 5). Most hemangiomas demonstrated homogenous enhancement (6/9, 67%). Conclusion: Triple arterial MRI using the 4D THRIVE-CENTRA-keyhole technique is feasible in despite of the relatively low detection rate, and is thus, helpful for the characterization of focal liver lesions.

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Contrast‐enhanced timing robust acquisition order with a preparation of the longitudinal signal component (CENTRA plus) for 3D contrast‐enhanced abdominal imaging

Cited by 26 publications

References 23 publications

Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI?

Can microvessel invasion of hepatocellular carcinoma be predicted by pre-operative MRI?

New acquisition techniques: fields of application

Triple Arterial Phase Hepatic MRI Using Four Dimensional T1-Weighted High Resolutions Imaging with Volume Excitation Keyhole Techniques: Feasibility and Initial Clinical Experience in Focal Liver Lesions

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