Contrast Enhanced Sonography of Focal Splenic Lesions with a Second-Generation Contrast Agent

Görg, Christian; Bert, Tillmann

doi:10.1055/s-2005-858904

Cited by 35 publications

(32 citation statements)

References 11 publications

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“…On CES splenic infarction as well as rupture is characterized by an unenhanced pattern.. Splenic lymphoma and metastases to the spleen usually demonstrates a reduced enhancement by CES in comparison to the surrounding splenic tissue enhancement as an in vivo reference [16]. Because of uncharacteristic imaging patterns clinical data and follow-up are important additives for definitive diagnosis [16]. Usually histologic confirmation is not necessary in these patients.…”

Section: The Incidentally Found Hypoechoic Splenic Tumormentioning

confidence: 97%

“…Areas of absent vascularization like hematomas, abscesses (Fig. 11), and infarcts are appropriate for CES investigation [14,16]. It makes a great visual impact to identify infarced areas by using CES.…”

Section: Pain In the Left Upper Quadrantmentioning

confidence: 99%

“…lymphoma, infarction, rupture, and metastasis) are more common and often demonstrate a hypoechoic pattern on B-mode sonography [1][2][3][4][5][6]. On CES splenic infarction as well as rupture is characterized by an unenhanced pattern.. Splenic lymphoma and metastases to the spleen usually demonstrates a reduced enhancement by CES in comparison to the surrounding splenic tissue enhancement as an in vivo reference [16]. Because of uncharacteristic imaging patterns clinical data and follow-up are important additives for definitive diagnosis [16].…”

Section: The Incidentally Found Hypoechoic Splenic Tumormentioning

confidence: 99%

“…Second-generation contrast agents like SonoVue® has been shown a high accumulation within the spleen [11,12]. Up to date there are only little data about contrast enhanced sonographic (CES) patterns of focal (peri-) splenic lesions [12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

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Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Görg¹,

Bert

2007

CMIR

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Objective: Ultrasound contrast agents in conjunction with contrast specific imaging techniques, are increasingly accepted in clinical use for diagnostic imaging in several organs. Contrast enhanced sonography (CES) of second generation contrast media have shown a spleen-specific uptake of the microbubble contrast agent. The aim of this review is to illustrate indications for the use of CES in patients with suspected (peri-)splenic pathology.Methods: This pictorial review based on the experience of transcutaneous CES in 180 consecutive adult patients with (peri-)splenic pathology diagnosed by B-mode sonography at an internal medicine center. CES studies were performed with a contrast-devoted unit (Acuson, Sequoia, Siemens medical solution) that had contrast-specific, continuous-mode software. A low mechanical index was used. A sulfur hexafluoride-based microbubble contrast medium (Sonovue ® , Bracco SpA, Milan, Italy) was injected.Results: On our experience there are six clinical conditions which indicates the use of CES for diagnosis of (peri-)splenic pathology: 1. the perisplenic tumor, 2. the small sized spleen, 3. the inhomogenous spleen of unknown cause, 4. the incidentally found hypoechoic splenic tumor, and 5. pain in the left upper quadrant, and 6. patients with blunt abdominal trauma. CES is of value 1. to diagnose or exclude accessory spleen, 2. to diagnose functional asplenia/hyposplenia, 3. to diagnose focal lesions in an inhomogenous spleen, 4. to diagnose high vascular splenic hemangioma, 5. to diagnose or exclude splenic infarction and splenic abscess, and 6. to diagnose splenic laceration.Conclusion: CES is of diagnostic value in several clinical circumstances to diagnose accessory spleen, functional asplenia, small sized splenic involvement, high vascular splenic hemangioma, and vascular splenic pathology like splenic infarction, splenic abscess, and splenic laceration.

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Section: The Incidentally Found Hypoechoic Splenic Tumormentioning

confidence: 97%

Section: Pain In the Left Upper Quadrantmentioning

confidence: 99%

Section: The Incidentally Found Hypoechoic Splenic Tumormentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Görg¹,

Bert

2007

CMIR

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“…L'échographie avec injection de produit de contraste optimisée dans son utilisation depuis l'arrivée des agents de contraste de deuxième génération permet une approche de la microvascularisation splénique, une amélioration du contraste lésionnel et, en raison d'une splénospécificité du SonoVue® (Bracco), produit actuellement le plus utilisé en échographie abdominale de routine, constatée par plusieurs équipes (13,14,16) une imagerie splénique spécifique.…”

Section: Introductionunclassified

Échographie de contraste de la rate

Bleuzen

Tranquart

Échographie De Contraste

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Sclerosing angiomatoid nodular transformation (SANT) of the spleen: Sonographic finding

Gutzeit

Stuckmann

Dommann-Scherrer

2009

J of Clinical Ultrasound

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Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized benign vascular lesion of the spleen. There is limited information regarding its imaging findings of this condition. Until now, the diagnosis was based on histopathologic examination of splenectomy specimens. We report the sonographic findings in a case of SANT of the spleen confirmed by ultrasound-guided core needle biopsy.

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Contrast Enhanced Sonography of Focal Splenic Lesions with a Second-Generation Contrast Agent

Abstract: Contrast-enhanced sonography is of diagnostic value in subgroups of patients with (peri-)splenic lesions (48%): including splenic infarction, splenic rupture, splenic haemangioma/splenoma, and accessory spleen.

Cited by 35 publications

References 11 publications

Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Échographie de contraste de la rate

Sclerosing angiomatoid nodular transformation (SANT) of the spleen: Sonographic finding

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