Contrast-enhanced power Doppler ultrasound in the diagnosis and follow-up of inflammatory abdominal masses in Crohn's disease

“…During an acute flare-up, however, vascular density appears to correlate with inflammatory activity [40]. The correlation of local bowel wall findings with clinical disease activity measured by CDAI remains contradictory for all imaging techniques [14,16,35,41].…”

Section: Discussionmentioning

confidence: 99%

Evaluating bowel wall vascularity in Crohn’s disease: a comparison of dynamic MRI and wideband harmonic imaging contrast-enhanced low MI ultrasound

et al. 2006

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This was a prospective comparison of dynamic MRI (1.5 T) and echo-signal enhanced ultrasound in evaluating vascularization in thickened bowel walls cases of Crohn's disease. Twenty-one patients with histologically confirmed Crohn's disease and bowel wall diameters >5 mm were examined by MRI and ultrasound (US). MR sequences: T1w fl2D, T2w, FLASH T1w post-contrast media (CM) applications with fat saturation were used. Dynamic Turbo-FLASH T1w sequences were acquired in the area of maximal thickening of the ileal wall every 1.5 s post-CM application for a total duration of 1 min. US was performed after the application of 1.2 ml of echo-signal enhancer. Contrast uptake was measured by the semiquantitative score and brightness analysis in regions of interest (ROI). Clinical and laboratory findings including Crohn's disease activity indices were documented; MRI and US parameters were correlated. The length of sonographically documented lesions (122+/-75 mm) correlated significantly with the length of thickened bowel segments in MRI (128+/-76 mm; r=0.466; P=0.033). The maximum percent signal enhancement in the terminal ileum at ultrasound (217.5+/-100.1%) showed a high correlation with the findings of MRI (262+/-108%; r=0.623; P=0.003). With both methods, a plateau phase was observed. US and MRI are capable of evaluating local vascularization in the bowel wall objectively.

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“…Mehrere Studien [Esteban et al 2003, Maconi et al 2003, 2007, Parente et al 2004, Castiglione et al 2004, Kratzer et al 2004, Kunihiro et al 2004, Fraquelli et al 2005, Mackalski et al 2006 [Arienti et al 2000, Hirche et al 2002, Pascu et al 2004, Hagiu et al 2007]. [Parente et al 2002, Maconi et al 2003, Neye et al 2004, Pascu et al 2004].…”

Section: Dopplershifts Sowie Ausgeprägter Inter-und Intraindividuellementioning

confidence: 99%

Prospektiver Vergleich von Power-Dopplersonographie und Ileokoloskopie in der Aktivitätsbewertung bei Patienten mit Morbus Crohn

Neye¹

2015

Z Gastroenterol

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Contrast-enhanced power Doppler ultrasound in the diagnosis and follow-up of inflammatory abdominal masses in Crohn's disease

Abstract: We conclude that contrast-enhanced power Doppler ultrasound is a sensitive method for the detection of small abdominal inflammatory masses and for differential diagnosis between phlegmon and abscess.

Cited by 51 publications

References 13 publications

Contrast–enhanced ultrasonography in Crohn’s disease

Contrast–enhanced ultrasonography in Crohn’s disease

Evaluating bowel wall vascularity in Crohn’s disease: a comparison of dynamic MRI and wideband harmonic imaging contrast-enhanced low MI ultrasound

Prospektiver Vergleich von Power-Dopplersonographie und Ileokoloskopie in der Aktivitätsbewertung bei Patienten mit Morbus Crohn

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