“…In our patient, these features contributed to the identification of a precise lesion site in the oculomotor nerve, as shown in the reconstructed images using curved and coronal MPRs. Our findings in the present patient suggest that not only heavily T2-weighted imaging, but also 3D fast SPGR in 3D gradient-echo sequences can be useful for detecting intracavernous lesions (10).…”
We herein present the case of a 38-year-old woman with left-sided oculomotor paralysis with ocular pain that developed after a respiratory infection. Her serum was positive for IgM against GM2 and GalNAc-GD1a gangliosides and cytomegalovirus. Thin-slice magnetic resonance imaging revealed enhanced abnormal tissue located primarily in the superolateral part of the left-sided cavernous sinus, which corticosteroids subsequently obscured with immediate resolution of the patient's ocular symptoms. These clinical features were consistent with those of Tolosa-Hunt syndrome (THS). Our findings in the present patient suggest that cytomegalovirus may provoke granuloma formation in the cavernous sinus, as reported in other various organs, thereby leading to the development of THS.
“…In our patient, these features contributed to the identification of a precise lesion site in the oculomotor nerve, as shown in the reconstructed images using curved and coronal MPRs. Our findings in the present patient suggest that not only heavily T2-weighted imaging, but also 3D fast SPGR in 3D gradient-echo sequences can be useful for detecting intracavernous lesions (10).…”
We herein present the case of a 38-year-old woman with left-sided oculomotor paralysis with ocular pain that developed after a respiratory infection. Her serum was positive for IgM against GM2 and GalNAc-GD1a gangliosides and cytomegalovirus. Thin-slice magnetic resonance imaging revealed enhanced abnormal tissue located primarily in the superolateral part of the left-sided cavernous sinus, which corticosteroids subsequently obscured with immediate resolution of the patient's ocular symptoms. These clinical features were consistent with those of Tolosa-Hunt syndrome (THS). Our findings in the present patient suggest that cytomegalovirus may provoke granuloma formation in the cavernous sinus, as reported in other various organs, thereby leading to the development of THS.
“…SOFS is manifested by the spread of cavernous sinus infection or inflammation to the orbital apex, or focal infection, inflammation, tumor and trauma. Detailed careful morphological evaluation, for example fast‐imaging employing steady‐state acquisition (FIESTA), and serological screening including antiganglioside antibody, might be required to rule out Tolosa–Hunt syndrome . Focal infection is sometimes not reflected in the blood tests and culture studies.…”
Section: Discussionmentioning
confidence: 99%
“…Detailed careful morphological evaluation, for example fast-imaging employing steady-state acquisition (FIESTA), and serological screening including antiganglioside antibody, might be required to rule out Tolosa-Hunt syndrome. 2,3 Focal infection is sometimes not reflected in the blood tests and culture studies. Thoughtless use of corticosteroids can worsen the patient's prognosis.…”
A 62-year-old woman who was prescribed prednisolone and cyclosporine for uveitis developed right blepharoptosis, diplopia and hypesthesia of superficial sensation of the trigeminal nerve V1 domain. Preserved right visual acuity led to a diagnosis of superior orbital fissure syndrome. We could not find any abnormalities on computed tomography except for right maxillary sinusitis associated with calcification. No infectious agents were detected in the blood or cerebrospinal fluid. We concluded that maxillary aspergillus, which was proven histopathologically after surgery, caused superior orbital fissure syndrome through the ophthalmic veins. Surgical excision of the lesion and voriconazole administration resulted in complete remission. To the best of our knowledge, there have been no other reports of superior orbital fissure syndrome caused by maxillary aspergillus sinusitis. The calcified sinusitis suggested fungal infections, which allowed us to avoid using corticosteroids.
“…These include trauma to the skull base in this region, vascular abnormalities such as carotidcavernous fistula and aneurysms, neoplasms such as pituitary adenoma, meningioma, lymphoma and metastasis, and inflammation around cavernous sinus and orbital apex which may induce cavernous sinus thrombosis. [123] Other causes include diabetic ophthalmoplegia, ophthalmoplegic migraine, sarcoidosis, eosinophilic granuloma, Wegner's granulomatosis and orbital pseudotumor. [34]…”
Section: Introductionmentioning
confidence: 99%
“…Modern imaging particularly magnetic resonance imaging (MRI) made it possible to study the lesions in the cavernous sinus and orbital apex responsible for this syndrome and other causes of painful ophthalmoplegia with high precision. [2]…”
Purpose:To highlight the role of constructive interference steady state (CISS) magnetic resonance imaging (MRI) in the diagnosis of Tolosa-Hunt Syndrome (THS).Case Report:We describe a case of THS in a 55-year-old woman presenting with left painful opthalmoplegia that was diagnosed by CISS MRI. Patient responded to steroid treatment and the lesion resolved.Conclusion:Imaging with MRI can help in making the diagnosis of THS by demonstrating an enhancing soft tissue lesion in the cavernous sinus and orbital apex resolving with steroids. CISS MRI is a sensitive sequence for diagnosis and follow-up imaging in THS.
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