Contrast echocardiography is superior to tissue harmonics for assessment of left ventricular function in mechanically ventilated patients

Kornbluth, Murray; Liang, David; Brown, Phillip P.; Gessford, Ellen; Schnittger, Ingela

doi:10.1067/mhj.2000.107175

Cited by 58 publications

(28 citation statements)

References 9 publications

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“…The modification of label was preceded by a grassroots advocacy group of clinicians (2,3), the publications of peer-reviewed data studies (4), and a realistic understanding of the probable risk-benefit relationship for contrast-enhanced echocardiography in patients (5)(6)(7)8).…”

mentioning

confidence: 99%

A Retrospective Comparison of Mortality in Critically Ill Hospitalized Patients Undergoing Echocardiography With and Without an Ultrasound Contrast Agent

Exuzides

Main

Colby

et al. 2010

JACC: Cardiovascular Imaging

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mentioning

confidence: 99%

A Retrospective Comparison of Mortality in Critically Ill Hospitalized Patients Undergoing Echocardiography With and Without an Ultrasound Contrast Agent

Exuzides

Main

Colby

et al. 2010

JACC: Cardiovascular Imaging

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“…Kornbluth et al evaluated the benefits of performing transthoracic echocardiography incrementally with fundamental tissue harmonic imaging and harmonic imaging combined with intravenous Optison in 50 consecutive mechanically ventilated patients in ICU [37].A total of 850 segments were either poor or not seen and 78% of these improved to good or excellent quality with contrast echocardiography versus 23% with tissue harmonics. Conversion of nondiagnostic to diagnostic imaging occurred in 85% of patients with contrast echocardiography versus 15% of patients with tissue harmonics.…”

Section: Contrast Echocardiography In the Intensive Care Unit Settingmentioning

confidence: 96%

Contrast Echocardiography for Left Ventricular Opacification

Eleid

Khandheria²,

Sengupta³

2004

Contrast Echocardiography in Clinical Practice

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Accurate assessment of left ventricular (LV) function is of paramount importance in clinical cardiology. Although the LV contraction and relaxation occur in a complex threedimensional format, changes in two-dimensional regional and global LV geometry during a cardiac cycle provide a reliable estimate of the overall LV function. This information is obtained comprehensively during realtime two-dimensional echocardiography by quantifying the extent of wall thickening, endocardial motion and serial changes in LV sizes and volumes. Accurate echo cardiographic interpretation, however, necessitates a proper delineation of the blood-endocardial interface and is not found adequately in a significant proportion (10%-20%) of patients referred for routine echocardiographic evaluation in clinical practice [ 1]. Suboptimal image quality in these patients results from a variety of factors including obesity, lung disease or chest wall deformities, thereby obviating an optimal application and utilization of cardiac ultrasound. Alternate techniques have emerged in the last decade for improving the diagnostic yield of echocardiography in such patients and include modalities like tissue harmonic imaging, contrast echocardiography and Doppler imaging for myocardial motion [2][3][4][5][6][7]. This chapter highlights the concepts and application of intravenous contrast for LV opacification, its clinical utility and relative merits in assessing structural and functional abnormalities of the left ventricle. Concepts and TechniqueGas bubbles interact complexly with incident ultrasound beams. Ultrasonic waves not only get reflected at the gas-liquid interface but are also modified in amplitude and frequency due to rapid bubble oscillations [8,9]. The ultrasound beam therefore encounters a wider scattering and frequency modulation with contrast agents than red-blood cells and hence echoes returning from bubbles effectively delineate the blood pool-endocardial interface [8,9]. J. L. Zamorano et al., Contrast Echocardiography in Clinical Practice

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“…Left ventricular opacification with contrast echo (CE) is currently proposed as an alternative technique to improve the analysis of global and regional function both at rest and during DSE [17][18][19][20]. Most [21][22][23][24][25]. This comparison has never been investigated during a stress test.…”

Section: Introductionmentioning

confidence: 99%

Head to head comparison of transesophageal and transthoracic contrast-enhanced echocardiography during dobutamine administration for the detection of coronary artery disease

Cosyns

Lancellotti

Camp

et al. 2008

International Journal of Cardiology

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Contrast echocardiography is superior to tissue harmonics for assessment of left ventricular function in mechanically ventilated patients

Cited by 58 publications

References 9 publications

A Retrospective Comparison of Mortality in Critically Ill Hospitalized Patients Undergoing Echocardiography With and Without an Ultrasound Contrast Agent

A Retrospective Comparison of Mortality in Critically Ill Hospitalized Patients Undergoing Echocardiography With and Without an Ultrasound Contrast Agent

Contrast Echocardiography for Left Ventricular Opacification

Head to head comparison of transesophageal and transthoracic contrast-enhanced echocardiography during dobutamine administration for the detection of coronary artery disease

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